Home 2018-01-15T09:54:10+00:00

Prof. dr. Heleen Riper

VU University Amsterdam, Faculty of Behavioural and Movement Sciences, Section of Clinical Psychology. Amsterdam, the Netherlands.

GGZinGeest, Amsterdam, the Netherlands.

Honorable Professor, University of Southern Denmark, Denmark.

Chair Triple-E (EMGO+ E-HEALTH EXCELLENCE), Amsterdam, the Netherlands.

Past President International Society for Research on Internet Interventions (ISRII)


International Scientific Publications in Peer Reviewed Journals

Publications in 2018

(last update 15 Januarz 2018)

  • Carlbring P, Andersson G, Cuijpers P, Riper H, & Hedman-Lagerlöf E. (2017). Internet-based vs. face-to-face cognitive behavior therapy for psychiatric and somatic disorders: An updated systematic review and meta-analysis. Cognitive Behaviour Therapy, 47(1), 1-18. doi:10.1080/16506073.2017.1401115
  • Kolovos S, van Dongen JM, Riper H, Buntrock C, Cuijpers P, Ebert DD, … & Bosmans JE. (2018). Cost effectiveness of guided internet-based interventions for depression in comparison with control conditions: An individual-participant data meta-analysis. Depression and Anxiety. doi:10.1002/da.22714
  • Klein NS, Kok GD, Burger H, van Valen E, Riper H, Cuijpers P, … & Bockting CL. (2018). No sustainable effects of an internet-based relapse prevention program over 24 months in recurrent depression: Primary outcomes of a randomized controlled trial. Psychotherapy and Psychosomatics, 87(1), 55-57. doi:10.1159/000485039

Publications in 2017

  • Boß L, Lehr D, Schaub MP, Castro RP, Riper H, Berking M, & Ebert DD. (2017). Efficacy of a web‐based intervention with and without guidance for employees with risky drinking: results of a three‐arm randomized controlled trial. Addiction. doi:10.1111/add.14085
  • Boumparis N, Karyotaki E, Schaub MP, Cuijpers P, & Riper H. (2017). Internet interventions for adult illicit substance users: A meta‐analysis. Addiction, 112, 1521-1532. doi:10.1111/add.13819
  • Buntrock C, Berking M, Smit F, Lehr D, Nobis S, Riper H, Cuijpers P, & Ebert DD. (2017).  Preventing depression in adults with subthreshold depression: Health-economic evaluation alongside a pragmatic randomized controlled trial of a web-based intervention. Journal of Medical Internet Research, 19(1), e5. doi:10.2196/jmir.6587
  • Cuijpers P, Kleiboer A, Karyotaki E, & Riper H. (2017). Internet and mobile interventions for depression: Opportunities and challenges. Depression and Anxiety, 34(7), 596-602. doi:10.1002/da.22641
  • Ebert DD, Buntrock C, Lehr D, Smit F, Riper H, Baumeister H, … & Berking M. (2017). Effectiveness of web- and mobile-based treatment of subthreshold depression with adherence-focused guidance. A single-blind randomised controlled trial. Behavior Therapy. doi:10.1016/j.beth.2017.05.004
  • Ebert DD, Kählke F, Buntrock C, Berking M, Smit F, Heber E, Baumeister H, Funk B, Riper H & Lehr D. (2017). A health economic outcome evaluation of an internet-based mobile-supported stress management intervention for employees. Scandinavian Journal of Work, Environment & Health. doi:10.5271/sjweh.3691
  • Ebert DD, Nobis S, Lehr D, Baumeister H, Riper H, Auerbach RP, Snoek F, Cuijpers P, & Berking M. (2017). The 6-month effectiveness of internet-based guided self-help for depression in adults with type 1 and 2 diabetes mellitus. Diabetic Medicine, 34(1), 99-107. doi: 10.1111/dme.13173
  • Erbe D, Eichert HC, Riper H, & Ebert DD. (2017). Blending face-to-face and internet-based interventions for the treatment of mental disorders in adults: Systematic review. Journal of Medical Internet Research, 19(9), e306. doi:10.2196/jmir.6588
  • Heber E, Ebert DD, Lehr D, Cuijpers P, Berking M, Nobis S, & Riper H. (2017). The benefit of web- and computer-based interventions for stress: A systematic review and meta-analysis. Journal of Medical Internet Research, 19(2), e32. doi:10.2196/jmir.5774
  • Karyotaki E, Riper H, & Cuijpers P. (2017). Internet-based self-help interventions for depression in routine care—Reply. JAMA Psychiatry, 74(8), 853. doi:10.1001/jamapsychiatry.2017.1406
  • Karyotaki E, Riper H, Twisk J, Hoogendoorn A, Kleiboer A, Mira A, . . . & Cuijpers P. (2017). Efficacy of self-guided internet-based cognitive behavioral therapy in the treatment of depressive symptoms: A meta-analysis of individual participant data. JAMA Psychiatry, 74(4), 351-359. doi:10.1001/jamapsychiatry.2017.0044
  • Kolovos S, Bosmans JE, Riper H, Chevreul K, Coupé VM, & van Tulder, MW. (2017). Model-based economic evaluation of treatments for depression: A systematic literature review. PharmacoEconomics-Open, 1-17. doi:10.1007/s41669-017-0014-7
  • Kolovos S, Bosmans JE, van Dongen JM, van Esveld B, Magai D, van Straten A, van der Feltz-Cornelis C, van Steenbergen-Weijenburg KM, Huijbregts KM, van Marwijk H, Riper H, & van Tulder MW. (2017). Utility scores for different health states related to depression: Individual participant data analysis. Quality of Life Research, 26(7), 1649-1658. doi:10.1007/s11136-017-1536-2
  • Kolovos S, van Tulder MW, Cuijpers P, Prigent A, Chevreul K, Riper H, & Bosmans JE. (2017). The effect of treatment as usual on major depressive disorder: A meta-analysis. Journal of Affective Disorders, 210, 72-81. doi:10.1016/j.jad.2016.12.013. Review.
  • Lau HM, Smit JH, Fleming TM, & Riper H. (2017). Serious Games for mental health: Are they accessible, feasible, and effective? A systematic review and meta-analysis. Frontiers in Psychiatry, 7, 209. doi:10.3389/fpsyt.2016.00209. Review.
  • Lin J, Sander L, Paganini S, Schlicker S, Ebert D, Berking M, … & Riper H. (2017). Effectiveness and cost-effectiveness of a guided internet- and mobile-based depression intervention for individuals with chronic back pain: Protocol of a multi-centre randomised controlled trial. BMJ Open, 7(12), e015226. doi:10.1136/bmjopen-2016-015226
  • Mikus A, Hoogendoorn M, Rocha A, Gama J, Ruwaard J, & Riper H. (2017). Predicting short term mood developments among depressed patients using adherence and ecological momentary assessment data. Internet Interventions. doi:10.1016/j.invent.2017.10.001
  • Mohr DC, Riper H, & Schueller SM. (2017). A solution-focused research approach to achieve an implementable revolution in digital mental health. JAMA Psychiatry. doi:10.1001/jamapsychiatry.2017.3838
  • Nuij C, Van Ballegooijen W, Ruwaard J, de Beurs D, O’Connor R, Smit J, Riper H, Kerkhof A. (2017). Smartphone-based safety planning and self-monitoring for suicidal patients: A conceptual basis for the CASPAR (Continuous Assessment for Suicide Prevention and Research) study. Preprints, 2017040103. doi:10.20944/preprints201704.0103.v1
  • Provoost S, Lau HM, Ruwaard J, & Riper H. (2017). Embodied conversational agents in clinical psychology: A scoping review. Journal of Medical Internet Research, 19(5), e151. doi:10.2196/jmir.6553
  • Topooco N, Riper H, Araya R, Berking M, Brunn M, Chevreul K, … & Andersson G.  (2017). Attitudes towards digital treatment for depression: A European stakeholder survey. Internet Interventions, 8, 1-9. doi:10.1016/j.invent.2017.01.001
  • Van de Ven P, O’Brien H, Henriques R, Klein M, Msetfi R, Nelson J, … & Riper H, on behalf of the E-COMPARED Consortium. (2017). ULTEMAT: A mobile framework for smart ecological momentary assessments and interventions. Internet Interventions, 9, 74-81. doi:10.1016/j.invent.2017.07.001

Published in 2016

  • Asselbergs J, Ruwaard J, Ejdys M, Schrader N, Sijbrandij M, & Riper H. (2016) Mobile phone-based unobtrusive ecological momentary assessment of day-to-day mood: An explorative study. Journal of Medical Internet Research, 18(3), e72. doi:10.2196/jmir.5505
  • Bijker L, Kleiboer A, Riper H, Cuijpers P, & Donker T. (2016). E-care 4 caregivers – an online intervention for nonprofessional caregivers of patients with depression: Study protocol for a pilot randomized controlled trial. Trials, 17(1), 193. doi:10.1186/s13063-016-1320-6
  • Boß L, Lehr D, Reis D, Vis C, Riper H, Berking M, & Ebert DD. (2016) Reliability and validity of assessing user satisfaction with web-based health interventions. Journal of Medical Internet Research, 18(8), e234. doi:10.2196/jmir.5952
  • Buntrock C, Ebert DD, Lehr D, Smit F, Riper H, Berking M, & Cuijpers P. (2016). Effect of a web-based guided self-help intervention for prevention of major depression in adults with subthreshold depression: A randomized clinical trial. Jama, 315(17), 1854-1863. doi:10.1001/jama.2016.4326
  • Ebert DD, Donkin L, Andersson G, Andrews G, Berger T, Carlbring P, Rozenthal A, Choi I, Laferton JA, Johansson R, Kleiboer A, Lange A, Lehr D, Reins JA, Funk B, Newby J, Perini S, Riper H, Ruwaard J, Sheeber L, Snoek FJ, Titov N, Ünlü Ince B, van Bastelaar K, Vernmark K, van Straten A, Warmerdam L, Salsman N, & Cuijpers P. (2016). Does internet-based guided-self-help for depression cause harm? An individual participant data meta-analysis on deterioration rates and its moderators in randomized controlled trials. Psychological Medicine, 46(13), 2679-2693. doi:10.1017/S0033291716001562
  • Ebert DD, Heber E, Berking M, Riper H, Cuijpers P, Funk B, & Lehr D. (2016). Self-guided internet-based and mobile-based stress management for employees: Results of a randomised controlled trial. Occupational and Environmental Medicine, 73(5), 315-323. doi:10.1136/oemed-2015-103269
  • Ebert DD, Lehr D, Heber E, Riper H, Cuijpers P, & Berking M. (2016) Internet- and mobile-based stress management for employees with adherence-focused guidance: Efficacy and mechanism of change. Scandinavian Journal of Work, Evironment & Health, 42(5), 382-394. doi:10.5271/sjweh.3573
  • Ebert DD, Nobis S, Lehr D, Baumeister H, Riper H, Auerbach RP, Snoek F, Cuijpers P, & Berking M. (2016). The 6-month effectiveness of internet-based guided self-help for depression in adults with type 1 and 2 diabetes mellitus. Diabetic Medicine, 34(1), 99-107. doi:10.1111/dme.13173
  • Fleming TM, de Beurs D, Khazaal Y, Gaggioli A, Riva G, Botella C, Baños RM, Aschieri F, Bavin LM, Kleiboer A, Merry S, Lau HM, & Riper H. (2016). Maximizing the impact of e-therapy and serious gaming: Time for a paradigm shift. Frontiers in Psychiatry, 7, 65. doi:10.3389/fpsyt.2016.00065. eCollection 2016. Review.
  • Heber E, Lehr D, Ebert DD, Berking M, & Riper H. (2016). Web-based and mobile stress management intervention for employees: A randomized controlled trial. Journal of Medical Internet Research, 18(1), e21. doi:10.2196/jmir.5112
  • Kemmeren LL, van Schaik DJ, Riper H, Kleiboer AM, Bosmans JE, & Smit JH. (2016). Effectiveness of blended depression treatment for adults in specialised mental healthcare: Study protocol for a randomised controlled trial. BMC Psychiatry, 16(1), 113. doi:10.1186/s12888-016-0818-5
  • Kleiboer A, Smit J, Bosmans J, Ruwaard J, Andersson G, Topooco N, … & Riper H. (2016). European COMPARative Effectiveness research on blended Depression treatment versus treatment-as-usual (E-COMPARED): Study protocol for a randomized controlled, non-inferiority trial in eight European countries. Trials, 17(1), 387. doi:10.1186/s13063-016-1511-1
  • Kooistra LC, Ruwaard J, Wiersma JE, van Oppen P, van der Vaart R, van Gemert-Pijnen L, & Riper H.(2016). Development and initial evaluation of blended cognitive behavioural treatment for major depression in routine specialized mental health care. Internet Interventions, 4, 61-71. doi:10.1016/j.invent.2016.01.003
  • Mathiasen K, Riper H, Ehlers LH, Valentin JB, & Rosenberg NK. (2016). Internet-based CBT for social phobia and panic disorder in a specialised anxiety clinic in routine care: Results of a pilot randomised controlled trial. Internet Interventions, 4, 92-98. doi:10.1016/j.invent.2016.03.001
  • Mol M, Dozeman E, van Schaik DJ, Vis CP, Riper H, & Smit JH. (2016). The therapist’s role in the implementation of internet-based cognitive behavioural therapy for patients with depression: Study protocol. BMC Psychiatry, 16(1), 338. doi:10.1186/s12888-016-1045-9
  • Nobis S, Lehr D, Berking M, Baumeister H, Riper H, Snoek F, & Ebert DD. (2016). Langzeiteffekte eines Online-Trainings zur Reduktion von depressiven Beschwerden für Personen mit Diabetes Mellitus Typ 1 und Typ 2 – Ergebnisse einer randomisiert-klinischen Studie nach 12 Monaten. Diabetologie und Stoffwechsel, 11(S 01), 89. doi:10.1055/s-0036-1580836
  • Patrick K, Hekler EB, Estrin D, Mohr DC, Riper H, Crane D, Godino J, & Riley WT. (2016). The pace of technologic change: Implications for digital health behavior intervention research. American Journal of Preventive Medicine, 51(5), 816-824. doi:10.1016/j.amepre.2016.05.001
  • Schaub MP, Blankers M, Lehr D, Boss L, Riper H, Dekker J, Goudriaan AE, Maier LJ, Haug S, Amann M, Dey M, Wenger A, & Ebert DD. (2016). Efficacy of an internet-based self-help intervention to reduce co-occurring alcohol misuse and depression symptoms in adults: Study protocol of a three-arm randomised controlled trial. BMJ Open, 6(5), e011457. doi:10.1136/bmjopen-2016-011457
  • Schuurmans J, Van der Linden JL, Van Ballegooijen W, Ruwaard J, Stek ML, Smit JH, & Riper H. (2016). Tablet-based support for older adults with severe mood disorders treated in an ambulatory geriatric psychiatry setting: Protocol of a feasibility study of the eCare@Home platform. Internet Interventions, 6, 22–28. doi:10.1016/j.invent.2016.09.001
  • Thiart H, Ebert DD, Lehr D, Nobis S, Buntrock C, Berking M, Smit F, & Riper H. (2016). Internet-based cognitive behavioral therapy for insomnia: A health economic evaluation. Sleep, 39(10), 1769. doi:10.5665/sleep.6152
  • Van Ballegooijen W, Riper H, Cuijpers P, van Oppen P, & Smit JH. (2016). Validation of online psychometric instruments for common mental health disorders: A systematic review. BMC Psychiatry, 16(1), 45. doi:10.1186/s12888-016-0735-7. Review.
  • Van Ballegooijen W, Ruwaard J, Karyotaki E, Ebert DD, Smit JH, & Riper H. (2016). Reactivity to smartphone-based ecological momentary assessment of depressive symptoms (MoodMonitor): Protocol of a randomised controlled trial. BMC Psychiatry, 16(1), 359. doi:10.1186/s12888-016-1065-5
  • Van Breda W, Pastor J, Hoogendoorn M, Ruwaard J, Asselbergs J, & Riper H. (2016). Exploring and comparing machine learning approaches for predicting mood over time. Conference Paper:  KES Conference on Innovation in Medicine and Healthcare, At Tenerife, Spain.
  • Yardley L, Spring BJ, Riper H, Morrison LG, Crane DH, Curtis K, Merchant GC, Naughton F, & Blandford A. (2016). Understanding and promoting effective engagement with digital behavior change interventions. American Journal of Preventive Medicine, 51(5), 833-842. doi:10.1016/j.amepre.2016.06.015
  • Zarski AC, Lehr D, Berking M, Riper H, Cuijpers P, & Ebert DD. (2016). Adherence to internet-based mobile-supported stress management: A pooled analysis of individual participant data from three randomized controlled trials. Journal of Medical Internet Research, 18(6), e146. doi:10.2196/jmir.4493

International Scientific Publications in Peer Reviewed Journals, published in 2015

  • Boß L, Lehr D, Berking M, Riper H, Schaub MP, & Ebert DD. (2015). Evaluating the (cost-)effectiveness of guided and unguided internet-based self-help for problematic alcohol use in employees, a three arm randomized controlled trial. BMC Public Health, 15(1), 1043. doi:10.1186/s12889-015-2375-0
  • Buntrock C, Ebert DD, Lehr D, Riper H, Smit F, Cuijpers P, & Berking M. (2015). Effectiveness of a web-based cognitive behavioural intervention for subthreshold depression: Pragmatic randomised controlled trial. Psychotherapy and Psychosomatics, 84(6), 348-358. doi:10.1159/000438673
  • Cuijpers P & Riper H. (2015). Internet interventions for depressive disorders: An overview. Revista De Psicopatología y Psicología Clínica, 19(3), 209-216. doi:10.5944/rppc.vol.19.num.3.2014.13902
  • De Wit J, Dozeman E, Ruwaard J, Alblas J, & Riper H. (2015). Web-based support for daily functioning of people with mild intellectual disabilities or chronic psychiatric disorders: A feasibility study in routine practice. Internet Interventions, 2(2), 161-168. doi:10.1016/j.invent.2015.02.007
  • Ebert DD, Berking M, Thiart H, Riper H, Laferton JA, Cuijpers P, Sieland B, & Lehr D. (2015). Restoring depleted resources: Efficacy and mechanisms of change of an internet-based unguided recovery training for better sleep and psychological detachment from work. Health Psychology, 34(S), 1240. doi:10.1037/hea0000277
  • Ebert DD, Zarski AC, Christensen H, Stikkelbroek Y, Cuijpers P, Berking M, & Riper H. (2015). Internet and computer-based cognitive behavioral therapy for anxiety and depression in youth: A meta-analysis of randomized controlled outcome trials. PLoS One, 10(3), e0119895. doi:10.1371/journal.pone.0119895
  • Jones M, Ebert DD, Jacobi C, Beintner I, Berger T, Görlich D, Schaub MP, Riper H, Schmidt U, Baños R, Botella C, & ICare Consortium (2015). Why didn’t patients use it? Engagement is the real story in Gilbody et al. (2015), not effectiveness. BMJ Online. (www.bmj.com/content/351/bmj.h5627/rr-4).
  • Karyotaki E, Kleiboer A, Smit F, Turner DT, Pastor AM, Andersson G, Berger T, Botella C, Breton JM, Carlbring P, Christensen H, de Graaf E, Griffiths K, Donker T, Farrer L, Huibers MJ, Lenndin J, Mackinnon A, Meyer B, Moritz S, Riper H, Spek V, Vernmark K, & Cuijpers P. (2015). Predictors of treatment dropout in self-guided web-based interventions for depression: An ‘individual patient data’ meta-analysis. Psychological Medicine, 45(13), 2717-2726. doi:10.1017/S0033291715000665
  • Kleiboer A, Donker T, Seekles W, van Straten A, Riper H, & Cuijpers P. (2015). A randomized controlled trial on the role of support in internet-based problem solving therapy for depression and anxiety. Behaviour Research and Therapy, 72, 63-71. doi:10.1016/j.brat.2015.06.013
  • Kok G, Burger H, Riper H, Cuijpers P, Dekker J, van Marwijk H, Smit F, Beck A, & Bockting CL. (2015). The three-month effect of mobile internet-based cognitive therapy on the course of depressive symptoms in remitted recurrently depressed patients: Results of a randomized controlled trial. Psychotherapy and Psychosomatics, 84(2), 90-99. doi:10.1159/000369469
  • Nobis S, Ebert DD, Lehr D, Riper H, Snoek F, Baumeister H, & Berking M. (2015). Langzeit-Effektivitäts-Analyse eines internetbasierten Programmes für Personen mit Diabetes mellitus Typ 1 und Typ 2 zur Reduktion von depressiven Beschwerden – Ergebnisse anhand einer randomisierten klinischen Studie. Diabetologie und Stoffwechsel 10(S 01), P136. doi:10.1055/s-0035-1549642
  • Nobis S, Lehr D, Ebert DD, Baumeister H, Snoek F, Riper H, & Berking M. (2015). Efficacy of a web-based intervention with mobile phone support in treating depressive symptoms in adults with type 1 and type 2 diabetes: A randomized controlled trial. Diabetes Care, 38(5), 776-783. doi:10.2337/dc14-1728
  • Romijn G, Riper H, Kok R, Donker T, Goorden M, van Roijen LH, Kooistra L, van Balkom A, & Koning J. (2015). Cost-effectiveness of blended vs. face-to-face cognitive behavioural therapy for severe anxiety disorders: Study protocol of a randomized controlled trial. BMC Psychiatry, 15(1), 311. doi:10.1186/s12888-015-0697-1
  • Thiart H, Lehr D, Ebert DD, Berking M, & Riper H. (2015). Log in and breathe out: Internet-based recovery training for sleepless employees with work-related strain – results of a randomized controlled trial. Scandinavian Journal of Work, Environment & Health, 41(2), 164-174. doi:10.5271/sjweh.3478
  • Vis C, Kleiboer A, Prior R, Bønes E, Cavallo M, Clark SA, Dozeman E, Ebert D, Etzelmueller A, Favaretto G, Zabala AF, Kolstrup N, Mancin S, Mathiassen K, Myrbakk VN, Mol M, Jimenez JP, Power K, van Schaik A, Wright C, Zanalda E, Pederson CD, Smit J, & Riper H. (2015). Implementing and up-scaling evidence-based eMental health in Europe: The study protocol for the MasterMind project. Internet Interventions, 2(4). doi:10.1016/j.invent.2015.10.002

 International Scientific Publications in Peer Reviewed Journals, published in 2014

  • Andersson G, Cuijpers P, Carlbring P, Riper H, & Hedman E. (2014). Guided internet-based vs. face-to-face cognitive behavior therapy for psychiatric and somatic disorders: A systematic review and meta-analysis. World Psychiatry, 13(3), 288-295. doi:10.1002/wps.20151
  • Bolier L, Maio C, Smit F, Westerhof GJ, Haverman M, Walburg JA, Riper H, & Bohlmeijer E. (2014). Cost-effectiveness of online positive psychology: Randomized controlled trial. Journal of Positive Psychology, 9(5), 460-471. doi:10.1080/17439760.2014.910829
  • Buntrock C, Ebert DD, Lehr D, Cuijpers P, Riper H, Smit F, & Berking M. (2014). Evaluating the efficacy and cost-effectiveness of web-based indicated prevention of major depression: Design of a randomised controlled trial. BMC Psychiatry, 14(1), 25. doi:10.1186/1471-244X-14-25
  • Ebenfeld L, Kleine Stegemann S, Lehr D, Ebert DD, Jazaieri H, van Ballegooijen W, Funk B, Riper H, & Berking M. (2014). Efficacy of a hybrid online training for panic symptoms and agoraphobia: Study protocol for a randomized controlled trial. Trials, 15(1), 427. doi:10.1186/1745-6215-15-427
  • Ebert DD, Lehr D, Baumeister H, Boß L, Riper H, Cuijpers P, Reins JA, Buntrock C, & Berking M. (2014). GET.ON Mood Enhancer: Efficacy of internet-based guided self-help compared to psychoeducation for depression: An investigator-blinded randomised controlled trial. Trials, 15(1), 39. doi:10.1186/1745-6215-15-39
  • Ebert DD, Lehr D, Boß L, Riper H, Cuijpers P, Andersson G, Thiart H, Heber E, & Berking M. (2014). Efficacy of an internet-based problem-solving training for teachers: Results of a randomized controlled trial. Scandinavian Journal of Work, Environment & Health, 40(6), 582-596. doi:10.5271/sjweh.3449
  • Ebert DD, Lehr D, Smit F, Zarski AC, Riper H, Heber E, Cuijpers P, & Berking M. (2014). Efficacy and cost-effectiveness of minimal guided and unguided internet-based mobile supported stress-management in employees with occupational stress: A three-armed randomised controlled trial. BMC Public Health, 14(1), 807. doi:10.1186/1471-2458-14-807
  • Emmelkamp PM, David D, Beckers T, Muris P, Cuijpers P, Lutz W, Andersson G, Araya R, Banos Rivera RM, Barkham M, Berking M, Berger T, Botella C, Carlbring P, Colom F, Essau C, Hermans D, Hofmann SG, Knappe S, Ollendick TH, Raes F, Rief W, Riper H, Van Der Oord S, & Vervliet B. (2014). Advancing psychotherapy and evidence-based psychological interventions. International Journal of Methods in Psychiatric Research, 23(S1), 58-91. doi:10.1002/mpr.1411
  • Guiry JJ, van de Ven P, Nelson J, Warmerdam L, & Riper H. (2014). Activity recognition with smartphone support. Medical Engineering & Physics, 36(6), 670-675. doi:10.1016/j.medengphy.2014.02.009
  • Heber E, Lehr D, Riper H, & Berking B (2014). Emotionsregulation: Überblick und kritische Reflexion des aktuellen Forschungsstandes. Zeitschrift für Klinische Psychologie und Psychotherapie, 43(3), 147-161. doi:10.1026/1616-3443/a000265
  • Kok G, van Rijsbergen G, Burger H, Elgersma H, Riper H, Cuijpers P, Dekker J, Smit F, & Bockting C. (2014). The scars of childhood adversity: Minor stress sensitivity and depressive symptoms in remitted recurrently depressed adult patients. PLoS One, 9(11), e111711. doi:10.1371/journal.pone.0111711
  • Kooistra LC, Wiersma JE, Ruwaard J, van Oppen P, Smit F, Lokkerbol J, Cuijpers P, & Riper H. (2014). Blended vs. face-to-face cognitive behavioural treatment for major depression in specialized mental health care: Study protocol of a randomized controlled cost-effectiveness trial. BMC Psychiatry, 14(1), 290. doi:10.1186/s12888-014-0290-z
  • Kramer J, Conijn B, Oijevaar P, & Riper H. (2014). Effectiveness of a web-based solution-focused brief chat treatment for depressed adolescents and young adults: Randomized controlled trial. Journal of Medical Internet Research, 16(5), e141. doi:10.2196/jmir.3261
  • Riper H, Andersson G, Hunter SB, de Wit J, Berking M, & Cuijpers P. (2014). Treatment of comorbid alcohol use disorders and depression with cognitive-behavioural therapy and motivational interviewing: A meta-analysis. Addiction, 109(3), 394-406. doi:10.1111/add.12441
  • Riper H, Blankers M, Hadiwijaya H, Cunningham J, Clarke S, Wiers R, Ebert D, & Cuijpers P. (2014). Effectiveness of guided and unguided low-intensity internet interventions for adult alcohol misuse: A meta-analysis. PLoS One, 9(6), e99912. doi:10.1371/journal.pone.0099912
  • Ünlü Ince B, Fassaert T, de Wit M, Cuijpers P, Smit J, Ruwaard J, & Riper H. (2014). The relationship between acculturation strategies and depressive and anxiety disorders in Turkish migrants in the Netherlands. BMC Psychiatry, 14(1), 252. doi:10.1186/s12888-014-0252-5
  • Ünlü Ince B, Riper H, van ‘t Hof E, Cuijpers P. (2014). The effects of psychotherapy on depression among racial-ethnic minority groups: A metaregression analysis. Psychiatric Services, 65(5), 612-617. doi:10.1176/appi.ps.201300165
  • Van Ballegooijen W, Cuijpers P, van Straten A, Karyotaki E, Andersson G, Smit JH, & Riper H. (2014). Adherence to internet-based and face-to-face cognitive behavioural therapy for depression: A meta-analysis. PLoS One, 9(7), e100674. doi:10.1371/journal.pone.0100674
  • Van der Vaart R, Witting M, Riper H, Kooistra L, Bohlmeijer ET, & van Gemert-Pijnen L. (2014). Blending online therapy into regular face-to-face therapy for depression: Content, ratio and preconditions according to patients and therapists using a Delphi study. BMC Psychiatry, 14(1), 355. doi:10.1186/s12888-014-0355-z
  • Wiencke C, Lehr D, Ebert DD, Sieland B, Riper H, & Berking M. (2014). Internetbasierte Ansätze in der Prävention und Behandlung von depressiven Beschwerden bei Jugendlichen und jungen Erwachsenen. Praxis der Kinderpsychologie und Kinderpsychiatrie, 63(5), 395-415. doi:10.13109/prkk.2014.63.5.395
  • Wirtz CM, Hofmann SG, Riper H, & Berking M. (2014). Emotion regulation predicts anxiety over a five-year interval: A cross-lagged panel analysis. Depression and Anxiety, 31(1), 87-95. doi:10.1002/da.22198
  • Wittchen HU, Knappe S, Andersson G, Araya R, Banos Rivera RM, Barkham M, Bech P, Beckers T, Berger T, Berking M, Berrocal C, Botella C, Carlbring P, Chouinard G, Colom F, Csillag C, Cujipers P, David D, Emmelkamp PM, Essau CA, Fava GA, Goschke T, Hermans D, Hofmann SG, Lutz W, Muris P, Ollendick TH, Raes F, Rief W, Riper H, Tossani E, van der Oord S, Vervliet B, Haro JM, & Schumann G. (2014). The need for a behavioural science focus in research on mental health and mental disorders. International Journal of Methods in Psychiatric Research, 23(S1), 28-40. doi:10.1002/mpr.1409

Earlier Publications –>


Principal Investigator (PI and Co-PI) awarded 2012 – 2017

  • 2017 – 2021: IMPLEMENTALL. eMental-Health Implementation, H2020, VUA & OUH, total 6.000.000 Euro, VUA, inGeest, RUG, 1.500.000 Euro.
  • 2016 – 2020: CASPAR, Suicidepreventie, ZonMw, VUA & inGeest, 400.000 Euro.
  • 2016 – 2020: INTERREG, eMental-health and transnational implementation platform North-West Europe. ARQ & VUA, total 5.313.000 Euro, VUA 800.000 Euro.
  • 2016 – 2020: Kansen voor West, eGGZ Implementatie Centrum, ARQ & VUA, total 2.217.000 Euro, VUA 300.000 Euro.
  • 2015 – 2019: Horizon 2020 PHC 23 (CO-PI, 2 stage): Safe and efficient, prevention-oriented health and care systems (2 stage) total 6.000.000, VUA 280.000 Euro (Co-PI; PI: prof. Corinna Jacobi, Technical University Dresden, Germany).
  • 2015 – 2018: ZonMw Doelmatigheid, DO 2015 Type 2A. Cost-utility and cost-effectiveness of blended eHealth treatment for severe anxiety disorders in secondary mental health care. (PI: Altrecht; Co PI VUA/inGEEST in collaboration with prof. dr. T. van Balkom, PhD student VUA), 341 K).
  • 2014 – 2016: PI: European Commission 7th Framework Programme for Research: Comparative effectiveness research (CER) in health systems and health services interventions. FP7-HEALTH-2013-INNOVATION. E-COMPARED (European Comparative Effectiveness Research on Internet-based Depression Treatment. Budget: € 5.827.000 of which € 1,4 million for VUA/inGeest and 800.000 for Leuphana/Marburg University.
  • 2014 -2016: PI-NL: Commission of the European Communities, CIP, DG CONNECT, Brussels, Belgium. MASTERMIND: MAnagement of mental health diSorders Through advancEd technology and seRvices – teleHealth for the MIND. Budget total € 7.000.000 of which 600.000 for VUA/GGZinGeest and € 600.000 for Marburg University/ Schon Clinic.
  • 2012 – 2015: PI-NL: Commission of the European Communities, Ambient Assisted Living Program, Brussels, Belgium. eMentalCare – daily life management and monitoring system (platform/solution) for elderly with mental disorders. Budget: € 400.000. (VUA & GGZinGeest).
  • 2012 – 2015: PI: ZonMw, Netherlands Organisation for Health Research and Development, Health Care Efficiency Research. Blended care for depression. Budget: € 137.039.
  • 2012: PI: ZonMw, Netherlands Organisation for Health Research and Devel- opment, Prevention Program Mental Health, the Netherlands. State of the art eMental-health (‘kennissynthese 2012’). Budget: € 25.000.
  • 2012 – 2014: PI: Health Insurers Innovation Foundation (Innovatiefonds Zorgverzekeraars), the Netherlands. Pilot-study blended care for depression in secondary care. In collaboration with GGZinGeest and Twente University. Budget: € 150.000
  • 2012- 2013: PI: Pameijer, Regional Health Service for People with Disabilities, the Netherlands. Feasibility study on online blended support for persons with severe psychological disorders in guided independent living settings. Budget: € 45.000.
  • 2012 – 2013: PI: ZonMw, Netherlands Organisation for Health Research and Development, Prevention Program Mental Health, the Netherlands. ICT4DEPRESSION/ Moodbuster-Light for subclinical and moderate depression. Budget: € 100.000.

Earlier Projects –>

Keynotes & Presentations

Invited key notes only


  1. Riper, H. (2016, 13 April). Patient, Science & Value driven eMental-Health – the good, the bad the better. Palo Alto: Palo Alto University eHealth Day.
  2. Riper, H. (2016, 22 April). Patient, Science & Value driven eMental-Health: Good, Better, Best. Amsterdam: eHealth EU Conference: Visit European Health Officer.
  3. Riper, H. (2016, 28 April). Patient, Science & Technology Driven Mental-Health. Esjberg (DK): SOCIAL IMPACT Conference.
  4. Riper, H. (2016, 30 May). Keynote by Skype: Theory, Patient & Data Driven – eMental-Health Research. Odense (DK): Conference Telepsychiatry Centre.
  5. Riper, H. (2016, 9 June). eMental Health – Klinische- Kosten- en Ecologische Effectiviteit. Groningen: Opleidingsinstituut PPO.
  6. Riper, H. (2016, 19 August). Thumbing for Mental Health. Basel: 5th International Conference on Families and Children with Parental Mental Health Challenges.
  7. Riper, H. (2016, 16 September). Duimen voor Psychische Aandoeningen? Zeist: Cancer Survivorship Task Force Meeting.
  8. Riper, H. (2016, 16 October). ‘Thumbing’ for Mental Health. Utrecht: Mobile Health Care Conference.
  9. Riper, H. (2016, 13 October). Blending Science driven eMental-Health in to Routine Health Care. Amsterdam: Amsterdam Public Health Research Institute.
  10. Riper, H. (2016, 12 November). Spotify Mental-Health for Depression and Anxiety: Personalise, Engage and Connect. Dallas: Int. Society for Traumatic Stress Studies. 32 nd Annual meeting.
  11. Riper, H. (2016, 22 November). eMental-Health for Depression and Anxiety: Personalise, Engage and Connect. Barcelona: World of Health IT/HIMSS.
  12. Riper, H. (2016, 25 November). eHealth & Seksuologie: van sexting tot safe seks. Amersfoort: Lustrumcongres NVVS, TVS, VVS: Seks 2.0. Implementatie Congres
  13. Riper, H (2016, 1 December). eMental Health: Good, Bad, Better. Utrecht, eHealth


  1. Riper, H. (2015, 8 April). Preventie die beklijft: Onderzoek dat leidt, Technologie die verleidt, Integratie die verblijdt & de patient die begrijpt! Rotterdam: Nederlands Congres Volksgezondheid.
  2. Riper, H. (2015, 1 May). Onderzoek dat leidt, De patient die begrijpt, Technologie die verleidt, Preventie die beklijft! Amsterdam, Nederland: VUmc: Preconceptiezorg, quo vadis?
  3. Riper, H. (2015, 16 May). Personalise, Engage and Connect, eMental-health for Common Mental Disorders. Warsaw, Poland: SWPS, University.
  4. Riper, H. (2015, 4 June). Geen toekomst voor de GGZ zonder eMental-health. Feit of Fictie? Arnhem, Nederland: DISCURA.
  5. Riper, H. (2015, 3 July). Social Psychiatry in the Age of Informatics. Geneva, Switzerland: 2nd European Congress for Social Psychiatry.
  6. Riper, H. (2014, 8 July). eMental-Health, Quantifying Patients, Therapist & Communities. Amsterdam, the Netherlands: UvA, International Summer School Addictions.
  7. Riper, H. (2015, 25 September). Digitale Behandeling van Probleemdrinken: de Effectiviteit Voorbij. Zwolle, Nederland: Motiverende gespreksvoering in Nederland, Hogeschool Windesheim.
  8. Riper, H. (2015, 30 September). Patient, Science & Value driven eMental-Health. Badhof Gastein, Austria: 18th European Health Forum Gastein.
  9. Riper, H. (2015, 21 October). eMental-health, the good, the bad and the better. Odense, Denmark: European Telemedicine Conference.
  10. Riper, H. (2015, 14 October). Spotify eMental-Health: Personalise, Engage & Connect. Porto, Portugal: Stop Depression: Instituto Superior da Maia (ISMAI).
  11. Riper, H. (2015, 17 November). Spotify Mental Health: Personalise, Engage, Connect. Eindhoven: Healthy Lifestyle Solutions Conference: Philips Group Innovation, Research.
  12. Riper, H. (2015, 1 december). eMental-Health: Good, Bad, Better. Utrecht, Jaarbeurs: eHealth Implementatie Congres, Bohn Stafleu van Loghum.
  13. Riper, H. (2015, 10 December). eMental Health: Denken én Doen. Utrecht, Nederland: IMPREEZE.

Earlier Presentations –>


My press appearances includes interviews for national television, radio and newspapers, magazines, websites and other national and international periodicals.

Press Highlights 2016

Press Highlights 2015

  • AD (29 december 2015) ‘Digitale behandeling razend populair in Nederland’. Marcia Nieuwenhuis.
  • NU.nl (29 december 2015) ‘Gebruik onlinetherapie gestegen in 2015’.
  • PZC (29 december 2015) ‘Hulp online groeit explosief’, Marcia Nieuwenhuis.
  • MindDistrict, Interview Heleen Riper, 15 years of eMental-health. Youtube: www.youtube.com/watch?v=qN00FKgXQUc (november 2015).
  • NPO Wetenschap, (4 november 2015) De Kennis van Nu: ‘Online gedragstherapie neemt hoge vlucht komende jaren’. Valentijn van der Lende.
  • Ad Valvas 3 (30 september 2015) ‘Therapeuten werken te weinig met nieuwe media.’ Welmoed Visser.
  • Smarthealth.nl: (10 september 2015) ‘Blog: de eerste hoogleraar e-Mental-Health in Nederland.’ Jorne Grolleman.
  • Counselling Magazine (8 september 2015) ‘Digitale psychologische hulpverlening nog beter in te zetten’.
  • Zorg &Welzijn (27 augustus 2015). ‘Digitale behandeling ggz biedt kansen’ Marianne Velsink.
  • GZ-psychologie 3 (april 2015) ‘Toekomst ggz ondenkbaar zonder eMental-health’ Jorn Hövels.
  • Cogis, Cogiscope 03 (maart 2015) ‘Implementatie van digitale zorg gaat langzaam.’ Maarten Dallinga.
  • Counselling Magazine: thema ‘E-Health’ (februari 2015) ‘Blended care heeft de toekomst’ Christine Beenhakker.

Press Highlights 2012 – 2014

  • Trouw (28 augustus 2014) ‘De psycholoog kijkt mee via internet’ Iris Pronk.
  • The Voice of the American Psychiatric Association and the Psychiatric Community (19 feb.2014) Equal Benefit for Minorities From Psychotherapy, Study Finds.
  • Leergang Sarphathi Initiatief, Academische Werkplaats Publieke Gezondheid (21 januari 2014). Interview met Heleen Riper “Smartphone is straks je toegang tot zorg” door Yvonne van Osch: http://sarfati.nl/?page_id=1114.
  • Young Gasteiners (2014). Blog, ‘Deploying eHealth, The time to hesitate is over!’ http://www.ehfg.org/conference.html.
  • European Parliament Magazine (22 Sept. 2014). Accelarating upscaling of eMental Health in Europe, H. Riper en J. Smit. 397, page 27. https://www.theparliamentmagazine.eu.
  • Altinget (velfaerdsteknologi, 9. december 2014) Ekspert, Heleen Riper: Online-behandling løser Sundhedsudfordringer.
  • Parliament magazine: https://www.theparliamentmagazine.eu/ : page 27/ issue397/22 Sept. 2014
  • PsychoPraktijk, december 2013 (6, nr. 5). Interview met Heleen Riper: ‘Blended behandelingen bepalen het komende e-mental health tijdperk’: 6 – 7.
  • Tracer (VUMC), november 2013. Blended care voor depressie, interview Heleen Riper.
  • Volkskrant, 30 oktober 2013, Geestelijke zorg kiest steeds vaker voor onlinehulp.
  • inDrukken (GGZ inGeest), juni 2013. ‘Een teachable moment via de smartphone-app’, interview met Heleen Riper.
  • Tracer (VUMC), juni 2013. Blended care voor depressie, interview Heleen Riper.
  • Zorgvisie / ICT, maart 2013, special issue Zorg & ICT beurs. Interview met Heleen Riper: ‘Elke zorginstelling beseft dat de toekomst bij e-health ligt’ door Mario Gibbels (cover story).
  • Zorgvisie/ ICT.Kennissynthese eMental-Health (2013): http://www.zorgvisie.nl/ICT/Nieuws/2013/5/Preventie-psychische-problemen-zonder-e-health-ondenkbaar-1271137W/
  • Algemeen Dagblad, 13 december 2012, Internettherapie vermindert suïcidegedachtes onder depressieve patiënten. Ingezonden brief: P. Cuijpers, H. Riper en F. Schalken.
  • UWV Magazine, Aan het lijntje gehouden (en toch geholpen), mei 2012.
  • Radiointerview: OBA Live – 2 mei 2012. Theodor Holman in gesprek met de hoofdgast van de avond Heleen Riper, over psychische zorg op afstand.
  • Zuidas Amsterdam, maart 2012, interview (http://www.zuidas.nl/interviews).
  • Plus Magazine, 12 februari 2012, M. v. Santen – Heleen Riper, interview.
  • Frankwatching.com: Wybo Vons, interview met Heleen Riper, 26 januari 2012 (www.frankwatching.com/archive/2012/).

Before 2012


Signaal, kwartaaluitgave nictiz, maart 2011. Heleen Riper en de kansen van e-mental health. ‘Iedereen heeft behoefte aan aandacht. Zelfs elektronisch’ De mogelijkheden van e-mental health zijn groot, zegt onderzoeker Heleen Riper. ‘Een scherm in je huiskamer met een virtuele coach, die zegt: Goedemorgen mevrouw Jansen, het is tijd om op te staan, kan veel hulp bieden.’ full text –>

De Pers 18 november 2010. ‘Social media maken zorg bereikbaar’ door Jules van der Leeuw
Voor ieder wissewasje naar je huisarts? Dat hoeft echt niet meer. Vanuit je luie stoel of je ziekbed iets vragen aan je behandelend arts? Medische vragen worden steeds vaker ‘uitbesteed’ dankzij Zorg 2.0: smart-phones, iPods en Twitter.
A tweet a day keeps the doctor away. full text –>

Volkskrant 15 november 2010 Digitaal hulp halen door Malou van Hintum
Woensdag vond in de Jaarbeurs in Utrecht het eerste congres over online hulpverlening plaats, een vorm van geestelijke hulp die inmiddels tien jaar bestaat. ‘En die de toekomst heeft’, zegt dr. Heleen Riper, onderzoeker e-mental health (VU Amsterdam, GGZInGeest) en keynote-speaker op het congres. full text –>

Volkskrant 30 januari 2010. ‘Mobiel stoppen’ door Ben van Raaij.
Slimme gadgets voor mobiel internet zijn hip. Je kunt er muziek mee herkennen, goedkoop boodschappen doen en je geparkeerde auto traceren, dus waarom niet stoppen met roken?… full text –>

Radio & Television

Radio 5 – OBA Live – 2 mei 2012. Theodor Holman in gesprek met de hoofdgast van de avond Heleen Riper, over psychische zorg op afstand. Steeds meer fysieke en psychische zorg vindt plaats via de computer. Hoe werkt dat, zorg op afstand? Prof. dr. Heleen Riper is expert op het gebied van e-health. Bekijk hier de videoregistratie.


NOS – 10 oktober 2009 – Radio 1 interview Psychologische hulp via internet succesvol Psychologische hulp via internet is een groot succes. Het is bewezen effectief, goedkoop en laagdrempelig. Nederland is koploper op het gebied van online geestelijke gezondheidszorg.

NOS televisie 10 oktober 2009

Radio 5 – OBA Live – 2 juli 2010. Joep Schrijvers in gesprek met Heleen Riper, directeur van I.COM (Onderdeel van Trimbos instituut: Centre of Mental Health & Technology). Heleen Riper is een rijzende ster op het gebied van e-health, psychische gezondheidszorg met nieuwe technieken en methoden via internet. Wat drijft haar, wat wil ze, wat is er mogelijk?

Luister hier het interview (55 min)

Online Media

Verslag Congres Social media in de Zorg 18 november 2010 door Erica van Harn – Kranenburg – Digitalezorg.nl
De aankomende 10 jaar is het van belang om de informatie communicatie technologieën in te zetten binnen de zorgsector. We moeten echt gaan nadenken over cliënt 3.0 die niet zonder professional 3.0 kan. Stel de cliënt centraal, participatie is van belang. Zorg ervoor dat hulpverlenen  plezierig is, gebruik daarom  serious gaming toepassingen. Denk eens aan de Funtheory! full text –>