Portretfoto Heleen Riper

Prof. dr. Heleen Riper

Full Professor eMental-Health/ Clinical Psychology VU & Amsterdam University Medical Centre (VUmc), Dept. of Psychiatry, Amsterdam, the Netherlands

Honorary Doctorate University of Bern, Switserland

Professor University of Southern Denmark, Telepsychiatry, Odense, Denmark

Chief Editor Digital Mental Health (Section Frontiers of Psychiatry & Digital Health)

President PAST International Society for Research on Internet Interventions (ISRII)

ORCID iD orcid.org/0000-0002-8144-8901

Web of Science ResearcherID: I-3101-2012


International Scientific Publications in Peer Reviewed Journals

Publications in 2024

(Last updated on March 6th, 2024; Newest first)

  • Jongeneel, A., Delespaul, P., Tromp, N., Scheffers, D., van der Vleugel, B., de Bont, P., Kikkert, M., Croes, C.F., Staring, A.B.P., Riper, H., van der Gaag, M., van den Berg, D. (2024) Effects on voice hearing distress and social functioning of unguided application of a smartphone app — A randomized controlled trial. Internet Interventions, vol 35, 2024, 100717  doi.org/10.1016/j.invent.2024.100717
  • Van Daele, T., Vis, C., Van Assche, E., Riper, H. (2024) Editorial: Dissemination, implementation and uptake of digital and technological interventions in practice. Frontiers in Digital Health vol 5.  doi.org/10.3389/fdgth.2023.1349545
  • Thielecke, J., Kuper, P., Ebert, D., Cuijpers, P., Smit, F., Riper, H., Lehr, D., Buntrock, C. (2024). Does outcome expectancy predict outcomes in online depression prevention? Secondary analysis of randomised-controlled trials. Health Expectations 27 (1) doi.org/10.1111/hex.13951
  • Vuijk, P; Bul, K; (…); Riper, H (2024) Effectiveness of a blended school-based mindfulness program for the prevention of co-rumination and internalizing problems in Dutch secondary school girls: a cluster randomized controlled trial. TRIALS 25 (1) WOS

Publications in 2023

  • Ciharova, M; Cuijpers, P; (…); Karyotaki, E (2023) Use of tailoring features and reasons for dropout in a guided internet-based transdiagnostic individually-tailored cognitive behavioral therapy for symptoms of depression and/or anxiety in college students. Internet Interventions-The Application of Information Technology in Mental and Behavioural Health 34 doi.org/10.1016/j.invent.2023.100646
  • Thielecke, J., Kuper, P., Ebert, D., Cuijpers, P., Smit, F., Riper, H., PhD, Lehr, D., Buntrock, C. (2024). Does outcome expectancy predict outcomes in online depression prevention? Secondary analysis of randomised-controlled trials. Health Expectations 27 (1) doi.org/10.1111/hex.13951
  • Müller, F., Verdam, M. G. E., Oort, F. J., Riper, H., van Straten, A., Verdonck-de Leeuw, I. M., Sprangers, M. A. G., & Knoop, H. (2023). Response Shift After Cognitive Behavioral Therapy Targeting Severe Fatigue: Explorative Analysis of Three Randomized Controlled Trials. International Journal of Behavioral Medicine, 30(4), 473–485. https://doi.org/10.1007/s12529-022-10111-8
  • Nuij, C., van Ballegooijen, W., Smit, A. C., de Beurs, D., de Winter, R. F. P., O’Connor, R. C., Kerkhof, A., Smit, J. H., & Riper, H. (2023). A proof of concept study on individual trends in suicidal ideation: an ecological momentary assessment study of 5 patients over three months. Journal for Person-Oriented Research, 9(1), 42-50. https://doi.org/10.17505/jpor.2023.25265
  • Smith, K. A., Blease, C., Faurholt-Jepsen, M., Firth, J., Van Daele, T., Moreno, C., Carlbring, P., Ebner-Priemer, U. W., Koutsouleris, N., Riper, H., Mouchabac, S., Torous, J., & Cipriani, A. (2023). Digital mental health: challenges and next steps. BMJ Mental Health, 26(1), e300670. https://doi.org/10.1136/bmjment-2023-300670
  • Hedman-Lagerlöf, E., Carlbring, P., Svärdman, F., Riper, H., Cuijpers, P., & Andersson, G. (2023). Therapist-supported Internet-based cognitive behaviour therapy yields similar effects as face-to-face therapy for psychiatric and somatic disorders: an updated systematic review and meta-analysis. World Psychiatry, 22(2), 305–314. https://doi.org/10.1002/wps.21088
  • Kemmeren, L. L., van Schaik, A., Draisma, S., Kleiboer, A., Riper, H., & Smit, J. H. (2023). Effectiveness of blended cognitive behavioral therapy versus treatment as usual for depression in routine specialized mental healthcare: E-COMPARED trial in the Netherlands. Cognitive Therapy and Research. Advance online publication. https://doi.org/10.1007/s10608-023-10363-y
  • Asselbergs, J., van Bentum, J., Riper, H., Cuijpers, P., Holmes, E., & Sijbrandij, M. (2023). A systematic review and meta-analysis of the effect of cognitive interventions to prevent intrusive memories using the trauma film paradigm. Journal of Psychiatric Research, 159, 116–129. https://doi.org/10.1016/j.jpsychires.2023.01.028
  • Vis, C., Schuurmans, J., Aouizerate, B., Atipei Craggs, M., Batterham, P., Bührmann, L., Calear, A., Cerga Pashoja, A., Christensen, H., Dozeman, E., Duedal Pedersen, C., Ebert, D. D., Etzelmueller, A., Fanaj, N., Finch, T. L., Hanssen, D., Hegerl, U., Hoogendoorn, A., Mathiasen, K., May, C., … Riper, H. (2023). Effectiveness of Self-guided Tailored Implementation Strategies in Integrating and Embedding Internet-Based Cognitive Behavioral Therapy in Routine Mental Health Care: Results of a Multicenter Stepped-Wedge Cluster Randomized Trial. Journal of Medical Internet Research, 25, e41532. https://doi.org/10.2196/41532
  • Oudshoorn, C. E. M., Frielink, N., Riper, H., & Embregts, P. J. C. M. (2023). Measuring working alliance and technical alliance from the perspective of healthcare professionals working with people with mild intellectual disabilities: adaptation, factor structure and reliability. Journal of Intellectual Disability Research, 67(1), 49–63. https://doi.org/10.1111/jir.12986

Publications in 2022

  • Alqahtani, F., Orji, R., Riper, H., McCleary, N., Witteman, H., & McGrath, P. (2022). Motivation-based approach for tailoring persuasive mental health applications. Behaviour & Information Technology. Advance online publication. https://doi.org/10.1080/0144929X.2022.2031296
  • Amarti, K., Schulte, M., Kleiboer, A., Van Genugten, C. R., Oudega, M., Sonnenberg, C., Gonçalves, G. C., Rocha, A., & Riper, H. (2022). Feasibility of Digital Cognitive Behavioral Therapy for Depressed Older Adults With the Moodbuster Platform: Protocol for 2 Pilot Feasibility Studies. JMIR Research Protocols11(10), e41445. https://doi.org/10.2196/41445
  • Augsburger, M., Kaal, E., Ülesoo, T., Wenger, A., Blankers, M., Haug, S., Ebert, D. D., Riper, H., Keough, M., Noormets, H., Schaub, M. P., & Kilp, K. (2022). Effects of a minimal-guided online intervention for alcohol misuse in Estonia: a randomized controlled trial. Addiction117(1), 108–117. https://doi.org/10.1111/add.15633
  • Baldwin, H., Loebel-Davidsohn, L., Oliver, D., Salazar de Pablo, G., Stahl, D., Riper, H., & Fusar-Poli, P. (2022). Real-World Implementation of Precision Psychiatry: A Systematic Review of Barriers and Facilitators. Brain Sciences12(7), 934. http://doi.org/10.3390/brainsci12070934
  • Bolinski, F., Kleiboer, A., Neijenhuijs, K., Karyotaki, E., Wiers, R., de Koning, L., Jacobi, C., Zarski, A. C., Weisel, K. K., Cuijpers, P., & Riper, H. (2022). Challenges in Recruiting University Students for Web-Based Indicated Prevention of Depression and Anxiety: Results From a Randomized Controlled Trial (ICare Prevent). Journal of Medical Internet Research24(12), e40892. https://doi.org/10.2196/40892
  • Boumparis, N., Haug, S., Abend, S., Billieux, J., Riper, H., & Schaub, M. P. (2022). Internet-based interventions for behavioral addictions: A systematic review, Journal of Behavioral Addictions, 11(3), 620-642. https://doi.org/10.1556/2006.2022.00054
  • Bührmann, L., Van Daele, T., Rinn, A., De Witte, N. A., Lehr, D., Aardoom, J. J., Loheide-Niesmann, L., Smit, J., & Riper, H. The feasibility of using Apple’s ResearchKit for recruitment and data collection: considerations for mental health research. Frontiers in Digital Health4, 978749. https://doi.org/10.3389/fdgth.2022.978749
  • Buntrock, C., Freund, J., Smit, F., Riper, H., Lehr, D., Boß, L., Berking, M., & Ebert, D. D. (2022). Reducing problematic alcohol use in employees: economic evaluation of guided and unguided web-based interventions alongside a three-arm randomized controlled trial. Addiction117(3), 611–622. https://doi.org/10.1111/add.15718
  • Hashemi, N. S., Skogen, J. C., Sevic, A., Thørrisen, M. M., Rimstad, S. L., Sagvaag, H., Riper, H., & Aas, R. W. (2022). A systematic review and meta-analysis uncovering the relationship between alcohol consumption and sickness absence. When type of design, data, and sickness absence make a difference. PLoS ONE17(1), e0262458. https://doi.org/10.1371/journal.pone.0262458
  • Jensen, E. S., Ladegaard, N., Mellentin, A. I., Ebert, D. D., Titzler, I., Araya, R., Cerga Pashoja, A., Hazo, J. B., Holtzmann, J., Cieslak, R., Smoktunowicz, E., Baños, R., Herrero, R., García-Palacios, A., Botella, C., Berger, T., Krieger, T., Holmberg, T. T., Topooco, N., Andersson, G., … Riper, H., Mathiasen, K. (2022). Effect of sleep disturbance symptoms on treatment outcome in blended Cognitive Behavioral Therapy for depression (E-COMPARED Study): Secondary analysis. Journal of Medical Internet Research24(3), e30231. https://doi.org/10.2196/30231
  • Jongeneel, A., Libedinsky, I., Reinbergen, A., Tromp, N., Delespaul, P., Riper, H., van der Gaag, M., & van den Berg, D. (2022). Momentary effects of Temstem, an app for voice-hearing individuals: Results from naturalistic data from 1048 users. Internet Interventions30, 100580. https://doi.org/10.1016/j.invent.2022.100580
  • Juniar, D., van Ballegooijen, W., Schulte, M., van Schaik, A., Passchier, J., Heber, E., Lehr, D., Sadarjoen, S. S., & Riper, H. (2022). A Web-Based Stress Management Intervention for University Students in Indonesia (Rileks): Feasibility Study Using a Pretest-Posttest Design. JMIR Formative Research6(7), e37278. https://doi.org/10.2196/37278
  • Karyotaki, E., Klein, A. M., Ciharova, M., Bolinski, F., Krijnen, L., de Koning, L., de Wit, L., van der Heijde, C. M., Ebert, D. D., Riper, H., Batelaan, N., Vonk, P., Auerbach, R. P., Kessler, R. C., Bruffaerts, R., Struijs, S., Wiers, R. W., & Cuijpers, P. (2022). Guided internet-based transdiagnostic individually tailored Cognitive Behavioral Therapy for symptoms of depression and/or anxiety in college students: A randomized controlled trial. Behaviour Research and Therapy150, 104028. https://doi.org/10.1016/j.brat.2021.104028
  • Mathiasen, K., Andersen, T. E., Lichtenstein, M. B., Ehlers, L. H., Riper, H., Kleiboer, A., & Roessler, K. K. (2022). The Clinical Effectiveness of Blended Cognitive Behavioral Therapy Compared With Face-to-Face Cognitive Behavioral Therapy for Adult Depression: Randomized Controlled Noninferiority Trial. Journal of Medical Internet Research24(9), e36577. https://doi.org/10.2196/36577
  • Mujcic, A., Blankers, M., Boon, B., Berman, A. H., Riper, H., van Laar, M., & Engels, R. (2022). Effectiveness, cost-effectiveness, and cost-utility of a digital alcohol moderation intervention for cancer survivors: Health economic evaluation and outcomes of a pragmatic randomized controlled trial. Journal of Medical Internet Research24(2), e30095. https://doi.org/10.2196/30095
  • Nuij, C., van Ballegooijen, W., de Beurs, D., de Winter, R. F. P., Gilissen, R., O’Connor, R. C., Smit, J. H., Kerkhof, A., & Riper, H. (2022). The feasibility of using smartphone apps as treatment components for depressed suicidal outpatients. Frontiers in Psychiatry13(September), 1–11. https://doi.org/10.3389/fpsyt.2022.971046
  • Paganini, S., Terhorst, Y., Sander, L. B., Lin, J., Schlicker, S., Ebert, D. D., Berking, M., Riper, H., & Baumeister, H. (2022). Internet- and mobile-based intervention for depression in adults with chronic back pain: A health economic evaluation. Journal of Affective Disorders308, 607–615. https://doi.org/10.1016/j.jad.2022.04.004
  • Sander, J., Bolinski, F., Diekmann, S., Gaebel, W., Günther, K., Hauth, I., Heinz, A., Kleiboer, A., Riper, H., Trost, N., Vlijter, O., Zielasek, J., & Gerlinger, G. (2022). Online therapy: an added value for inpatient routine care? Perspectives from mental health care professionals. European Archives of Psychiatry and Clinical Neuroscience272(1), 107–118. https://doi.org/10.1007/s00406-021-01251-1
  • Schouten, M., Christ, C., Dekker, J., Riper, H., Goudriaan, A. E., & Blankers, M. (2022). Digital interventions for people with co-occurring depression and problematic alcohol use: A systematic review and meta-analysis. Alcohol and Alcoholism57(1), 113–124. https://doi.org/10.1093/alcalc/agaa147
  • Schulte, M. H. J., Boumparis, N., Kleiboer, A., Wind, T. R., Olff, M., Huizink, A. C., & Riper, H. (2022). The effectiveness of a mobile intervention to reduce young adults’ alcohol consumption to not exceed low-risk drinking guidelines. Frontiers in Digital Health4, 1016714. https://doi.org/10.3389/fdgth.2022.1016714
  • Shorter, G., Bray, J., Heather, N., Berman, A. H., Giles, E. L., Clarke, M., Barbosa, C., O’Donnell, A., Holloway, A., Riper, H., Daeppen, J. B., Monteiro, M. G., Saitz, R., McNeely, J., McKnight-Eily, L., Cowell, A., Toner, P., & Newbury-Birch, D. (2022). Outcome reporting in brief intervention trials: Alcohol’ (ORBITAL) core outcome set: From international consensus to international use? Addiction Science & Clinical Practice17(SUPPL 1), O28.
  • Van Assche, E., Bonroy, B., Mertens, M., Van den Broeck, L., Desie, K., Bolinski, F., Amarti, K., Kleiboer, A., Riper, H., & Van Daele, T. (2022). E-mental health implementation in inpatient care: Exploring its potential and future challenges. Frontiers in Digital Health4, 1027864. https://doi.org/10.3389/fdgth.2022.1027864
  • van der Boom, B., Boumparis, N., Donker, T., de Beurs, D., Arntz, A., & Riper, H. (2022). Internet-delivered interventions for personality disorders – A scoping review. Internet Interventions28, 100525. https://doi.org/10.1016/j.invent.2022.100525
  • van der Boom, B., Lagemaat, A. P., Donker, T., Bos, J., Brand-de Wilde, O. M., Nikkels, K., de Beurs, D., Arntz, A. R., & Riper, H. (2022). Schematherapie via beeldbellen; crosssectioneel onderzoek onder therapeuten [Online schema therapy: a cross-sectional survey among Dutch therapists]. Tijdschrift voor Psychiatrie64(9), 609–616.
  • van Genugten, C. R., Schuurmans, J., Hoogendoorn, A. W., Araya, R., Andersson, G., Baños, R. M., Berger, T., Botella, C., Cerga Pashoja, A., Cieslak, R., Ebert, D. D., García-Palacios, A., Hazo, J. B., Herrero, R., Holtzmann, J., Kemmeren, L., Kleiboer, A., Krieger, T., Rogala, A., Titzler, I., … Riper, H. (2022). A data-driven clustering method for discovering profiles in the dynamics of major depressive disorder using a smartphone-based ecological momentary assessment of mood. Frontiers in Psychiatry13, 755809. https://doi.org/10.3389/fpsyt.2022.755809
  • Vis, C., Kleiboer, A., Mol, M., Pedersen, C. D., Finch, T., Smit, J., Riper, H., & MasterMind Consortium (2022). Organisational implementation climate in implementing internet-based cognitive behaviour therapy for depression. BMC Health Services Research22(1), 720. https://doi.org/10.1186/s12913-022-08041-y

Publications in 2021

  • Bolinski, F., Etzelmuller, A., De Witte, N. A. J., Van Beurden, C., Debard, G., Bonroy, B., Cuijpers, P., Riper, H., & Kleiboer, A. (2021). Physiological and self-reported arousal in virtual reality versus face-to-face emotional activation and cognitive restructuring in university students: A crossover experimental study using wearable monitoring. Behaviour Research and Therapy, 142, 103877. https://doi.org/10.1016/j.brat.2021.103877 
  • Boumparis, N., Schulte, M. H., Kleiboer, A., Huizink, A., & Riper, H. (2021). A Mobile Intervention to Promote Low-Risk Drinking Habits in Young Adults: Protocol for a Randomized Controlled Trial. JMIR Research Protocols, 10(6), e29750. https://doi.org/10.2196/29750 
  • Buntrock, C., Freund, J., Smit, F., Riper, H., Lehr, D., Boß, L., Berking, M., & Ebert, D. D. (2021). Reducing problematic alcohol use in employees: economic evaluation of guided and unguided web‐based interventions alongside a three‐arm randomized controlled trial. Addiction, 1–12. https://doi.org/10.1111/add.15718
  • Buntrock, C., Lehr, D., Smit, F., Horvath, H., Berking, M., Spiegelhalder, K., Riper, H., & Ebert, D. D. (2021). Guided Internet-Based Cognitive Behavioral Therapy for Insomnia: Health-Economic Evaluation From the Societal and Public Health Care Perspective Alongside a Randomized Controlled Trial. Journal of Medical Internet Research, 23(5), e25609. https://doi.org/10.2196/25609 
  • Ciharova, M., Furukawa, T. A., Efthimiou, O., Karyotaki, E., Miguel, C., Noma, H., Cipriani, A., Riper, H., & Cuijpers, P. (2021). Cognitive Restructuring, Behavioral Activation and Cognitive-Behavioral Therapy in the Treatment of Adult Depression: A Network Meta-Analysis. Journal of Consulting and Clinical Psychology, 89(6), 563-574. https://doi.org/10.1037/ccp0000654 
  • Ebenfeld, L., Lehr, D., Ebert, D. D., Stegemann, S. K., Riper, H., Funk, B., & Berking, M. (2021). Evaluating a Hybrid Web-Based Training Program for Panic Disorder and Agoraphobia: Randomized Controlled Trial. Journal of Medical Internet Research, 23(3), e20829. https://doi.org/10.2196/20829 
  • Ebert, D. D., Franke, M., Zarski, A. C., Berking, M., Riper, H., Cuijpers, P., Funk, B., & Lehr, D. (2021). Effectiveness and Moderators of an Internet-Based Mobile-Supported Stress Management Intervention as a Universal Prevention Approach: Randomized Controlled Trial. Journal of  Medical Internet Research, 23(12), e22107. https://doi.org/10.2196/22107 
  • Furukawa, T. A., Levine, S. Z., Buntrock, C., Ebert, D. D., Gilbody, S., Brabyn, S., Kessler, D., Bjorkelund, C., Eriksson, M., Kleiboer, A., van Straten, A., Riper, H., Montero-Marin, J., Garcia-Campayo, J., Phillips, R., Schneider, J., Cuijpers, P., & Karyotaki, E. (2021). How can we estimate QALYs based on PHQ-9 scores? Equipercentile linking analysis of PHQ-9 and EQ-5D. Evidence-Based Mental Health, 24(3), 97-101. https://doi.org/10.1136/ebmental-2020-300240 
  • Furukawa, T. A., Suganuma, A., Ostinelli, E. G., Andersson, G., Beevers, C. G., Shumake, J., Berger, T., Boele, F. W., Buntrock, C., Carlbring, P., Choi, I., Christensen, H., Mackinnon, A., Dahne, J., Huibers, M. J. H., Ebert, D. D., Farrer, L., Forand, N. R., Strunk, D. R., … Riper, H., … Cuijpers, P. (2021). Dismantling, optimising, and personalising internet cognitive behavioural therapy for depression: a systematic review and component network meta-analysis using individual participant data. Lancet Psychiatry, 8(6), 500-511. https://doi.org/10.1016/s2215-0366(21)00077-8 
  • Karyotaki, E., Efthimiou, O., Miguel, C., Bermpohl, F. M. G., Furukawa, T. A., Cuijpers, P., Riper, H., Patel, V., Mira, A., Gemmil, A. W., Yeung, A. S., Lange, A., Williams, A. D., Mackinnon, A., Geraedts, A., van Straten, A., Meyer, B., Björkelund, C., Knaevelsrud, C., . . . Forsell, Y. (2021). Internet-Based Cognitive Behavioral Therapy for Depression: A Systematic Review and Individual Patient Data Network Meta-analysis. JAMA Psychiatry, 78(4), 361-371. https://doi.org/10.1001/jamapsychiatry.2020.4364 
  • Kerber, A., Schaeuffele, C., Krieger, T., Urech, A., Riper, H., Berger, T., Boettcher, J., & Knaevelsrud, C. (2021). Differential Effects of Psychological Interventions in Online and Face-to-Face Settings on DSM-5 and ICD-11 Maladaptive Trait Domains: An Exploratory Pilot Study. Frontiers in Psychiatry, 12, 648367. https://doi.org/10.3389/fpsyt.2021.648367 
  • Klein, A., Wolters, N. E., Bol, E. J. M., Koelen, J., de Koning, L., Roetink, S. S. M., van Blom, J. J., Pronk, T., van der Heijde, C., Salemink, E., Bolinski, F., Riper, H., Karyotaki, E., Cuijpers, P., Schneider, S., Rapee, R. M., Vonk, P., & Wiers, R. W. (2021). Online computer or therapist-guided cognitive behavioral therapy in university students with anxiety and/or depression: Study protocol of a randomised controlled trial. BMJ Open, 11(11), e049554. https://doi.org/10.1136/bmjopen-2021-049554 
  • Nuij, C., van Ballegooijen, W., de Beurs, D., Juniar, D., Erlangsen, A., Portzky, G., O’Connor, R. C., Smit, J. H., Kerkhof, A., & Riper, H. (2021). Safety planning-type interventions for suicide prevention: meta-analysis. British Journal of Psychiatry, 219(2), 419-426. https://doi.org/10.1192/bjp.2021.50 
  • Oudshoorn, C. E. M., Frielink, N., Riper, H., & Embregts, P. J. C. M. (2021). Experiences of therapists conducting psychological assessments and video conferencing therapy sessions with people with mild intellectual disabilities during the COVID-19 pandemic. International Journal of Developmental Disabilities. https://doi.org/10.1080/20473869.2021.1967078 
  • Rahmadiana, M., Karyotaki, E., Schulte, M., Ebert, D. D., Passchier, J., Cuijpers, P., Berger, T., van Ballegooijen, W., Wimbarti, S., & Riper, H. (2021). Transdiagnostic Internet Intervention for Indonesian University Students With Depression and Anxiety: Evaluation of Feasibility and Acceptability. JMIR Mental Health, 8(3), e20036. https://doi.org/10.2196/20036 
  • Rasing, S. P. A., Stikkelbroek, Y. A. J., den Hollander, W., Riper, H., Dekoviec, M., Nauta, M. H., Creemers, D. H. M., Immink, M. C. P., Spuij, M., & Bodden, D. H. M. (2021). Pragmatic Quasi-Experimental Controlled Trial Evaluating the Outcomes of Blended CBT Compared to Face-to-Face CBT and Treatment as Usual for Adolescents with Depressive Disorders. International Journal of Environmental Research and Public Health, 18(6), 3102. https://doi.org/10.3390/ijerph18063102 
  • Romijn, G., Batelaan, N., Koning, J., van Balkom, A., de Leeuw, A., Benning, F., Hakkaart van Roijen, L., & Riper, H. (2021). Acceptability, effectiveness and cost-effectiveness of blended cognitive-behavioural therapy (bCBT) versus face-to-face CBT (ftfCBT) for anxiety disorders in specialised mental health care: A 15-week randomised controlled trial with 1-year follow-up. PLoS One, 16(11), e0259493. https://doi.org/10.1371/journal.pone.0259493 
  • Romijn, G., Provoost, S., Batelaan, N., Koning, J., van Balkom, A., & Riper, H. (2021). Does it blend? Exploring therapist fidelity in blended CBT for anxiety disorders. Internet Interventions, 25, 100418. https://doi.org/10.1016/j.invent.2021.100418 
  • Sander, J., Bolinski, F., Diekmann, S., Gaebel, W., Gunther, K., Hauth, I., Heinz, A., Kleiboer, A., Riper, H., Trost, N., Vlijter, O., Zielasek, J., & Gerlinger, G. (2021). Online therapy: an added value for inpatient routine care? Perspectives from mental health care professionals. European Archives of Psychiatry and Clinical Neuroscience. https://doi.org/10.1007/s00406-021-01251-1 
  • Schouten, M. J. E., Christ, C., Dekker, J. J. M., Riper, H., Goudriaan, A. E., & Blankers, M. (2021). Digital Interventions for People With Co-Occurring Depression and Problematic Alcohol Use: A Systematic Review and Meta-Analysis. Alcohol and Alcoholism, agaa147. https://doi.org/10.1093/alcalc/agaa147 
  • Schouten, M. J. E., Dekker, J. J. M., de Bruijn, T. Q., Ebert, D. D., Koomen, L. M., Kosterman, S. L. A., Riper, H., Schaub, M. P., Goudriaan, A. E., & Blankers, M. (2021). Effectiveness of a digital alcohol moderation intervention as an add-on to depression treatment for young adults: study protocol of a multicentre pragmatic randomized controlled trial. BMC Psychiatry, 21(1), 265. https://doi.org/10.1186/s12888-021-03222-1 
  • Schulte, M. H. J., Aardoom, J. J., Loheide-Niesmann, L., Verstraete, L. L. L., Ossebaard, H. C., & Riper, H. (2021). Effectiveness of eHealth Interventions in Improving Medication Adherence for Patients With Chronic Obstructive Pulmonary Disease or Asthma: Systematic Review. Journal of Medical Internet Research, 23(7), e29475. https://doi.org/10.2196/29475 
  • Shorter, G. W., Bray, J. W., Heather, N., Berman, A. H., Giles, E. L., Clarke, M., Barbosa, C., O’Donnell, A. J., Holloway, A., Riper, H., Daeppen, J. B., Monteiro, M. G., Saitz, R., McNeely, J., McKnight-Eily, L., Cowell, A., Toner, P., & Newbury-Birch, D. (2021). The “Outcome Reporting in Brief Intervention Trials: Alcohol” (ORBITAL) core outcome set: International consensus on outcomes to measure in efficacy and effectiveness trials of alcohol brief interventions. Journal of Studies on Alcohol and Drugs, 82(5), 638-646. 
  • van Genugten, C. R., Schuurmans, J., Hoogendoorn, A. W., Araya, R., Andersson, G., Baños, R., Botella, C., Cerga Pashoja, A., Cieslak, R., Ebert, D. D., García-Palacios, A., Hazo, J. B., Herrero, R., Holtzmann, J., Kemmeren, L., Kleiboer, A., Krieger, T., Smoktunowicz, E., Titzler, I., … Riper, H. (2021). Examining the theoretical framework of behavioral activation for major depressive disorder: Smartphone-based ecological momentary assessment study. JMIR Mental Health, 8(12), e32007. https://doi.org/10.2196/32007 
  • van Genugten, C. R., Schuurmans, J., van Ballegooijen, W., Hoogendoorn, A. W., Smit, J. H., & Riper, H. (2021). Discovering different profiles in the dynamics of depression based on real-time monitoring of mood: a first exploration. Internet Interventions, 26, 100437. https://doi.org/10.1016/j.invent.2021.100437 
  • Verdam, M. G. E., van Ballegooijen, W., Holtmaat, C. J. M., Knoop, H., Lancee, J., Oort, F. J., Riper, H., van Straten, A., Verdonck-de Leeuw, I. M., de Wit, M., van der Zweerde, T., & Sprangers, M. A. G. (2021). Re-evaluating randomized clinical trials of psychological interventions: Impact of response shift on the interpretation of trial results. PLoS One, 16(5), e0252035. https://doi.org/10.1371/journal.pone.0252035 

Publications in 2020

  • Aardoom, J. J., Loheide-Niesmann, L., Ossebaard, H. C., & Riper, H. (2020). Effectiveness of eHealth Interventions in Improving Treatment Adherence for Adults With Obstructive Sleep Apnea: Meta-Analytic Review. Journal of Medical Internet Research22(2), e16972. https://doi.org/10.2196/16972
  • Aarestrup, F. M., Albeyatti, A., Armitage, W. J., Auffray, C., Augello, L., Balling, R., …, Riper, H.,… & Van Oyen, H. (2020). Towards a European health research and innovation cloud (HRIC). Genome Medicine12(1), 1-14. https://doi.org/10.1186/s13073-020-0713-z
  • Bakker, A., Riper, H., & Olff, M. (2020). E-health applications in the field of traumatic stress.
  • Becker, D., Bremer, V., Funk, B., Hoogendoorn, M., Rocha, A., & Riper, H. (2020). Evaluation of a temporal causal model for predicting the mood of clients in an online therapy. Evidence-Based Mental Health23(1), 27-33. https://doi.org/10.1136/ebmental-2019-300135
  • Bolinski, F., Boumparis, N., Kleiboer, A., Cuijpers, P., Ebert, D. D., & Riper, H. (2020). The effect of e-mental health interventions on academic performance in university and college students: A meta-analysis of randomized controlled trials. Internet Interventions, 100321.  https://doi.org/10.1016/j.invent.2020.100321
  • Bonten, T. N., Rauwerdink, A., Wyatt, J. C., Kasteleyn, M. J., Witkamp, L., Riper, H., … & Chavannes, N. H. (2020). Online Guide for Electronic Health Evaluation Approaches: Systematic Scoping Review and Concept Mapping Study. Journal of Medical Internet Research22(8), e17774. https://doi.org/10.2196/17774
  • Bührmann, L., Schuurmans, J., Ruwaard, J., Fleuren, M., Etzelmüller, A., Piera-Jiménez, J., Batterham, P. J., …, Riper, H., …, & ImpleMentAll consortium (2020). Tailored implementation of internet-based cognitive behavioural therapy in the multinational context of the ImpleMentAll project: a study protocol for a stepped wedge cluster randomized trial. Trials21(1), 1-15. https://doi.org/10.1186/s13063-020-04686-4 
  • Ebenfeld, L., Stegemann, S. K., Lehr, D., Ebert, D. D., Funk, B., Riper, H., & Berking, M. (2020). A mobile application for panic disorder and agoraphobia: Insights from a multi-methods feasibility study. Internet Interventions19, 100296. https://doi.org/10.1016/j.invent.2019.100296
  • Etzelmueller, A., Vis, C., Karyotaki, E., …, Riper., H. & Ebert, D. D. (2020). Effects of Internet-Based Cognitive Behavioral Therapy in Routine Care for Adults in Treatment for Depression and Anxiety: Systematic Review and Meta-Analysis. Journal of Medical Internet Research, 22(8), e18100. https://doi.org/10.2196/18100
  • Friedl, N., Krieger, T., Chevreul, K., Hazo, J. B., Holtzmann, J., Hoogendoorn, M., …, Riper, H., & Berger, T. (2020). Using the Personalized Advantage Index for Individual Treatment Allocation to Blended Treatment or Treatment as Usual for Depression in Secondary Care. Journal of clinical medicine9(2), 490. https://doi.org/10.3390/jcm9020490
  • Gleeson, JFM., Riper, H., Alvarez-Jimenez, M. (2020). Transforming Youth Mental Health Treatment Through Digital Technology. Frontiers in Psychology, 11. https://doi.org/10.3389/fpsyt.2020.606433
  • Herrero, R., Vara, M., Miragall, M., Botella, C., García-Palacios, A., Riper, H., … & Baños, R. M. (2020). Working Alliance Inventory for Online Interventions-Short Form (WAI-TECH-SF): The Role of the Therapeutic Alliance between Patient and Online Program in Therapeutic Outcomes. International Journal of Environmental Research and Public Health17(17), 6169. https://doi.org/10.3390/ijerph17176169
  • Hu, M. X., Palantza, C., Setkowski, K., Gilissen, R., Karyotaki, E., Cuijpers, P., Riper, H., … & Calear, A. (2020). Comprehensive database and individual patient data meta-analysis of randomised controlled trials on psychotherapies reducing suicidal thoughts and behaviour: study protocol. https://doi.org/10.1136/bmjopen-2020-037566
  • Jongeneel, A., Aalbers, G., Bell, I., Fried, E. I., Delespaul, P., Riper, H., … & van den Berg, D. (2020). A time-series network approach to auditory verbal hallucinations: Examining dynamic interactions using experience sampling methodology. Schizophrenia researchhttps://doi.org/10.1016/j.schres.2019.10.055
  • Kaal, E., Schaub, M. P., Wenger, A., Ülesoo, T., Blankers, M., Haug, S., …, Riper, H., … & Kilp, K. (2020). Testing the efficacy of a minimal-guidance online self-help intervention for alcohol misuse in Estonia: study protocol of a randomized controlled trial. BMC Public Health20(1), 1-11. https://doi.org/10.1186/s12889-020-08791-6
  • Kooistra, L., Ruwaard, J., Wiersma, J., van Oppen, P., & Riper, H. (2020). Working Alliance in Blended Versus Face-to-Face Cognitive Behavioral Treatment for Patients with Depression in Specialized Mental Health Care. Journal of Clinical Medicine9(2), 347. https://doi.org/10.3390/jcm9020347
  • Mol, M., van Genugten, C., Dozeman, E., van Schaik, D. J., Draisma, S., Riper, H., & Smit, J. H. (2020). Why Uptake of Blended Internet-Based Interventions for Depression Is Challenging: A Qualitative Study on Therapists’ Perspectives. Journal of Clinical Medicine9(1), 91. https://doi.org/10.3390/jcm9010091
  • Mol, M., van Schaik, A., Dozeman, E., Ruwaard, J., Vis, C., Ebert, D. D., …, Riper, H., & Pedersen, C. D. (2020). Dimensionality of the system usability scale among professionals using internet-based interventions for depression: a confirmatory factor analysis. BMC psychiatry20(1), 1-10. https://doi.org/10.1186/s12888-020-02627-8
  • Provoost, S., Kleiboer, A., Ornelas, J., Bosse, T., Ruwaard, J., Rocha, A., … & Riper, H. (2020). Improving adherence to an online intervention for low mood with a virtual coach: study protocol of a pilot randomized controlled trial. Trials21(1), 1-12. https://doi.org/10.1186/s13063-020-04777-2
  • Schaub M. P., Berman A. H., López Pelayo H., Boumparis, N., Khadjesari, Z., Blankers, M., Gual, A., Riper, H., & Pas, L. (2020). e-INEBRIA Special Interest Group Roadmap to Best Practices for Practice and Research on Brief Digital Interventions for Problematic Alcohol and Illicit Drug Use. Journal of Medical Internet Research. 10.2196/20368. https://doi.org/10.2196/20368
  • Smoktunowicz, E., Barak, A., Andersson, G., Banos, R. M., Berger, T., Botella, C., … , Riper, H., & Carlbring, P. (2020). Consensus statement on the problem of terminology in psychological interventions using the internet or digital components. Internet Interventions21, 100331. https://doi.org/10.1016/j.invent.2020.100331
  • Titzler, I., Berking, M., Schlicker, S., Riper, H., & Ebert, D. D. (2020). Barriers and facilitators for referrals of primary care patients to blended internet-based psychotherapy for depression: A mixed methods study of general practitioners’ views. JMIR Mental Healthhttps://doi.org/10.2196/18642
  • van Genugten, C. R., Schuurmans, J., Lamers, F., Riese, H., Penninx, B. W., Schoevers, R. A., … , Riper, H., & Smit, J. H. (2020). Experienced Burden of and Adherence to Smartphone-Based Ecological Momentary Assessment in Persons with Affective Disorders. Journal of Clinical Medicine9(2), 322. https://doi.org/10.3390/jcm9020322
  • Vis, C., Bührmann, L., Riper, H., & Ossebaard, H. C. (2020). Health technology assessment frameworks for eHealth: A systematic review. International Journal of Technology Assessment in Health Care, 1-13. https://doi.org/10.1017/S026646232000015X
  • Wind, T. R., Rijkeboer, M., Andersson, G., & Riper, H. (2020). The COVID-19 pandemic: The ‘black swan’ for mental health care and a turning point for e-health. Internet Interventions. https://doi.org/10.1016/j.invent.2020.100317

Publications in 2019

  • Beecham, J., Bonin, E. M., Görlich, D., Baños, R., Beintner, I., Buntrock, C., … & Riper, H., …, & Jacobi C. (2019). Assessing the costs and cost-effectiveness of ICare internet-based interventions (protocol). Internet interventions16, 12-19. https://doi.org/10.1016/j.invent.2018.02.009
  • Boumparis, N., Loheide-Niesmann, L., Blankers, M., Ebert, D. D., Korf, D., Schaub, M. P., … & Riper, H. (2019). Short-and Long-Term Effects of Digital Prevention and Treatment Interventions for Cannabis Use Reduction: A Systematic Review and Meta-analysis. Drug and Alcohol Dependencehttps://doi.org/10.1016/j.drugalcdep.2019.03.016
  • Breedvelt, J. J., Zamperoni, V., Kessler, D., Riper, H., Kleiboer, A. M., Elliott, I., … & Bockting, C. L. (2019). GPs’ attitudes towards digital technologies for depression: an online survey in primary care. British Journal of General Practice69(680), e164-e170. https://doi.org/10.3399/bjgp18X700721
  • Bremer, V., Funk, B., & Riper, H. (2019). Heterogeneity Matters: Predicting Self-Esteem in Online Interventions Based on Ecological Momentary Assessment Data. Depression research and treatment2019https://doi.org/10.1155/2019/3481624
  • Jongeneel, A., van Veen, S. C., Scheffers, D., Riper, H., van den Hout, M. A., van der Gaag, M., & van den Berg, D. (2019). Linguistic dual tasking reduces emotionality, vividness and credibility of voice memories in voice-hearing individuals: Results from a controlled trial. Schizophrenia Researchhttps://doi.org/10.1016/j.schres.2019.11.048
  • Juniar, D., van Ballegooijen, W., Karyotaki, E., van Schaik, A., Passchier, J., Heber, E., … & Riper, H. (2019). Web-Based Stress Management Program for University Students in Indonesia: Systematic Cultural Adaptation and Protocol for a Feasibility Study. JMIR research protocols8(1), e11493. https://doi.org/10.2196/11493
  • Kählke, F., Buntrock, C., Smit, F., Berking, M., Lehr, D., Heber, E., … , Riper, H., & Ebert, D. D. (2019). Economic Evaluation of an Internet-Based Stress Management Intervention Alongside a Randomized Controlled Trial. JMIR Mental Health6(5), e10866. https://doi.org/10.2196/10866
  • Karyotaki, E., Furukawa, T. A., Efthimiou, O., Riper, H., & Cuijpers, P. (2019). Guided or self-guided internet-based cognitive–behavioural therapy (iCBT) for depression? Study protocol of an individual participant data network meta-analysis. BMJ open9(6), e026820. https://doi.org/10.1136/bmjopen-2018-026820
  • Karyotaki, E., Klein, A. M., Riper, H., Wit, L., Krijnen, L., Bol, E., …, & Cuijpers, P. (2019). Examining the effectiveness of a web-based intervention for symptoms of depression and anxiety in college students: study protocol of a randomised controlled trial. BMJ Open, 9(5), e028739. https://doi.org/10.1136/bmjopen-2018-028739
  • Kemmeren, L. L., van Schaik, A., Smit, J. H., Ruwaard, J., Rocha, A., Henriques, M., … & Riper, H. (2019). Unraveling the Black Box: Exploring Usage Patterns of a Blended Treatment for Depression in a Multicenter Study. JMIR mental health6(7), e12707. https://doi.org/10.2196/12707
  • Kooistra, L. C., Wiersma J. E., Ruwaard J., Neijenhuijs K., Lokkerbol J., van Oppen P., Smit F., & Riper, H.(2019). Cost and Effectiveness of Blended Versus Standard Cognitive Behavioral Therapy for Outpatients With Depression in Routine Specialized Mental Health Care: Pilot Randomized Controlled Trial. Journal of Medical Internet Research, 10, e14261. https://doi.org/10.2196/14261
  • Pot-Kolder, R., Jongeneel, A., & Riper, H. (2019). e-Health In M. van der Gaag & T. Staring (Eds.), Handboek psychose (pp. 248-255). Amsterdam: Uitgeverij Boom.
  • Provoost, S., Ruwaard, J., Breda, W. V., Riper, H., & Bosse, T. (2019). Validating automated sentiment analysis of online cognitive behavioral therapy patient texts: An exploratory study. Frontiers in psychology10, 1065. https://doi.org/10.3389/fpsyg.2019.01065
  • Rahmadiana, M., Karyotaki, E., Passchier, J., Cuijpers, P., van Ballegooijen, W., Wimbarti, S., & Riper, H. (2019). Guided internet-based transdiagnostic intervention for Indonesian university students with symptoms of anxiety and depression: A pilot study protocol. Internet interventions15, 28-34. https://doi.org/10.1016/j.invent.2018.11.002
  • Rasing, S. P., Stikkelbroek, Y. A., Riper, H., Dekovic, M., Nauta, M. H., Dirksen, C. D., … & Bodden, D. H. (2019). Effectiveness and cost-effectiveness of blended cognitive behavioral therapy in clinically depressed adolescents: Protocol for a pragmatic quasi-experimental controlled trial. JMIR research protocols8(10), e13434. https://doi.org/10.2196/13434
  • Romijn, G., Batelaan, N., Kok, R., Koning, J., van Balkom, A., Titov, N., & Riper, H. (2019). Internet-Delivered Cognitive Behavioral Therapy for Anxiety Disorders in Open Community Versus Clinical Service Recruitment: Meta-Analysis. Journal of Medical Internet Research, 21(4), e11706. https://doi.org/10.2196/11706
  • Schlicker, S., Weisel, K. K., Buntrock, C., Berking, M., Nobis, S., Lehr, D., … & Riper, H., & Ebert D. D. (2019). Do Nonsuicidal Severely Depressed Individuals with Diabetes Profit from Internet-Based Guided Self-Help? Secondary Analyses of a Pragmatic Randomized Trial. Journal of Diabetes Research2019, 2634094. https://doi.org/10.1155/2019/2634094
  • Skogen, J. C., Bøe, T., Thørrisen, M. M., Riper, H., & Aas, R. W. (2019). Sociodemographic characteristics associated with alcohol consumption and alcohol-related consequences, a latent class analysis of The Norwegian WIRUS screening study. BMC Public Health19(1), 1364. https://doi.org/10.1186/s12889-019-7648-6
  • Ünlü Ince, B., Gökçay, D., Riper, H., & Cuijpers P. (2019). Effectiveness of a Web- and Mobile-Guided Psychological Intervention for Depressive Symptoms in Turkey: Protocol for a Randomized Controlled Trial. JMIR Research Protocols, 8(4), e13239. https://doi.org/10.2196/13239
  • Van Ballegooijen, W., Eikelenboom, M., Fokkema, M., Riper, H., van Hemert, A. M., Kerkhof, A. J. F. M., Penninx, B. W. J. H., & Smit, J. H. (2018). Comparing factor structures of depressed patients with and without suicidal ideation, a measurement invariance analysis. Journal of Affective Disorders, 245, 180-187. https://doi.org/10.1016/j.jad.2018.10.108
  • Vis, C., Ruwaard, J., Finch, T., Rapley, T., de Beurs, D., van Stel, H., … & Riper, H., & Smit, J. (2019). Toward an Objective Assessment of Implementation Processes for Innovations in Health Care: Psychometric Evaluation of the Normalization Measure Development (NoMAD) Questionnaire Among Mental Health Care Professionals. Journal of Medical Internet Research21(2), e12376. https://doi.org/10.2196/12376
  • Weisel, K. K., Zarski, A. C., Berger, T., Krieger, T., Schaub, M. P., Moser, C. T., … & Riper, H., & Ebert, D. D. (2019). Efficacy and cost-effectiveness of guided and unguided internet-and mobile-based indicated transdiagnostic prevention of depression and anxiety (ICare Prevent): A three-armed randomized controlled trial in four European countries. Internet interventions16, 52-64. https://doi.org/10.1016/j.invent.2018.04.002

Publications in 2018

  • Asselbergs, J., Sijbrandij, M., Hoogendoorn, E., Cuijpers, P., Olie, L., Oved, K., … & Riper, H. (2018). Development and testing of TraumaGameplay: An iterative experimental approach using the trauma film paradigm. European Journal of Psychotraumatology9(1), 1424447. https://doi.org/10.1080/20008198.2018.1424447
  • Becker, D., van Breda, W., Funk, B., Hoogendoorn, M., Ruwaard, J., & Riper, H. (2018). Predictive modeling in e-mental health: A common language framework. Internet Interventions, 12, 57-67. https://doi.org/10.1016/j.invent.2018.03.002
  • Bijker, L., Kleiboer, A., Riper, H., Cuijpers, P., & Donker, T. (2018). A pilot randomized controlled trial of E-care for caregivers: An internet intervention for caregivers of depressed patients. Internet Interventions, 9, 88-99. https://doi.org/10.1016/j.invent.2017.06.003
  • Bremer, V., Mukherjee, A., Becker, D., Kolovos, S., Funk, B., Breda, W.V., Hoogendoorn, M., & Riper, H. (2018). Predicting therapy success and costs using baseline characteristics – An Approach for personalized treatment recommendations. Internet Interventions, 12, 100-104. https://doi.org/10.1016/j.invent.2017.08.003
  • Bolinski, F., Kleiboer, A., Karyotaki, E., Bosmans, J. E., Zarski, A. C., Weisel, K. K., … & Riper, H. (2018). Effectiveness of a transdiagnostic individually tailored internet-based and mobile-supported intervention for the indicated prevention of depression and anxiety (ICare Prevent) in Dutch college students: Study protocol for a randomised controlled trial. Trials19(1), 118. https://doi.org/10.1186/s13063-018-2477-y
  • Boß, L., Lehr, D., Schaub, M. P., Paz Castro, R., Riper, H., Berking, M., & Ebert, D. D. (2018). Efficacy of a web‐based intervention with and without guidance for employees with risky drinking: Results of a three‐arm randomized controlled trial. Addiction113(4), 635-646. https://doi.org/10.1111/add.14085
  • Carlbring, P., Andersson, G., Cuijpers, P., Riper, H., & Hedman-Lagerlöf, E. (2018). Internet-based vs. face-to-face cognitive behavior therapy for psychiatric and somatic disorders: An updated systematic review and meta-analysis. Cognitive Behaviour Therapy47(1), 1-18. https://doi.org/10.1080/16506073.2017.1401115
  • Ebert, D. D., Buntrock, C., Lehr, D., Smit, F., Riper, H., Baumeister, H., … & Berking, M. (2018). Effectiveness of web- and mobile-based treatment of subthreshold depression with adherence-focused guidance: A single-blind randomized controlled trial. Behavior Therapy, 49(1), 71-83. https://doi.org/10.1016/j.beth.2017.05.004
  • Ebert, D. D., Kählke, F., Buntrock, C., Berking, M., Smit, F., Heber, E., Baumeister, H., Funk, B., Riper, H., & Lehr, D. (2018). A health economic outcome evaluation of an internet-based mobile-supported stress management intervention for employees. Scandinavian Journal of Work, Environment & Health, 44(2), 171-182. https://doi.org/10.5271/sjweh.3691
  • Jongeneel, A., Scheffers, D., Tromp, N., Nuij, C., Delespaul, P., Riper, H., … & van den Berg, D. (2018). Reducing distress and improving social functioning in daily life in people with auditory verbal hallucinations: Study protocol for the ‘Temstem’ randomised controlled trial. BMJ Open8(3), e020537. https://doi.org/10.1136/bmjopen-2017-020537
  • Karyotaki, E., Ebert, D. D., Donkin, L., Riper, H., Twisk, J., Burger, S., … & Geraedts, A. (2018). Do guided internet-based interventions result in clinically relevant changes for patients with depression? An individual participant data meta-analysis. Clinical Psychology Review, 63, 80-92. https://doi.org/10.1016/j.cpr.2018.06.007
  • Karyotaki, E., Kemmeren, L., Riper, H., Twisk, J., Hoogendoorn, A., Kleiboer, A., … & Littlewood, E. (2018). Is self-guided internet-based cognitive behavioural therapy (iCBT) harmful? An individual participant data meta-analysis. Psychological Medicine, 1-11. https://doi.org/10.1017/S0033291718000648
  • Klein, N. S., Bockting, C. L., Wijnen, B., Kok, G. D., van Valen, E., Riper, H., … & Smit, F. (2018). Economic Evaluation of an Internet-Based Preventive Cognitive Therapy With Minimal Therapist Support for Recurrent Depression: Randomized Controlled Trial. Journal of Medical Internet Research, 20(11). e10437. https://doi.org/10.2196/10437
  • Klein, N. S., Kok, G. D., Burger, H., van Valen, E., Riper, H., Cuijpers, P., … & Bockting, C. L. (2018). No sustainable effects of an internet-based relapse prevention program over 24 months in recurrent depression: Primary outcomes of a randomized controlled trial. Psychotherapy and Psychosomatics87(1), 55-57. https://doi.org/10.1159/000485039
  • Kolovos, S., van Dongen, J. M., Riper, H., Buntrock, C., Cuijpers, P., Ebert, D. D., … & Bosmans, J. E. (2018). Cost effectiveness of guided internet-based interventions for depression in comparison with control conditions: An individual-participant data meta-analysis. Depression and Anxiety, 35(3), 209-219.https://doi.org/10.1002/da.22714
  • Kooistra, L. C., Wiersma, J. E., Ruwaard, J. J., Riper, H., Penninx, B. W. J. H., & van Oppen, P. (2018). Six-year healthcare trajectories of adults with anxiety and depressive disorders: Determinants of transition to specialised mental healthcare. Journal of Affective Disorders, 241, 226-234. https://doi.org/10.1016/j.jad.2018.07.072
  • Mathiasen, K., Riper, H., Andersen, T. E., & Roessler, K. K. (2018). Guided Internet-Based Cognitive Behavioral Therapy for Adult Depression and Anxiety in Routine Secondary Care: Observational Study. Journal of Medical Internet Research20(11). e10927. https://doi.org/10.2196/10927
  • Mikus, A., Hoogendoorn, M., Rocha, A., Gama, J., Ruwaard, J., & Riper, H. (2018). Predicting short term mood developments among depressed patients using adherence and ecological momentary assessment data. Internet Interventions, 12, 105-110. https://doi.org/10.1016/j.invent.2017.10.001
  • Mohr, D. C., Riper, H., & Schueller, S. M. (2018). A solution-focused research approach to achieve an implementable revolution in digital mental health. JAMA Psychiatry75(2), 113-114. https://doi.org/10.1001/jamapsychiatry.2017.3838
  • Mol, M., Dozeman, E., Provoost, S., van Schaik, A., Riper, H., & Smit, J. H. (2018). Behind the scenes of online therapeutic feedback in blended therapy for depression: Mixed-methods observational study. Journal of Medical Internet Research20(5), e174. https://doi.org/10.2196/jmir.9890
  • Nobis, S., Ebert, D. D., Lehr, D., Smit, F., Buntrock, C., Berking, M., … & Riper, H. (2018). Web-based intervention for depressive symptoms in adults with types 1 and 2 diabetes mellitus: A health economic evaluation. The British Journal of Psychiatry212(4), 199-206. https://doi.org/10.1192/bjp.2018.10
  • Nuij, C., van Ballegooijen, W., Ruwaard, J., de Beurs, D., Mokkenstorm, J., van Duijn, E., de Winter, R. F. P., O’Connor, R. C., Smit, J. H., Riper, H., & Kerkhof, A. (2018). Smartphone-based safety planning and self-monitoring for suicidal patients: Rationale and study protocol of the CASPAR (Continuous Assessment for Suicide Prevention And Research) study. Internet Interventions 13, 16-23. https://doi.org/10.1016/j.invent.2018.04.005
  • Provoost, S. J., Ruwaard, J. J., Neijenhuis, K., Bosse, T., & Riper, H. (2018). Mood mirroring with an embodied virtual agent: A pilot study into the relationship between personalized visual feedback and adherence. In Proceedings of the 16th International Conference on Practical Applications of Agents and Multi-Agent Systems, PAAMS’18, Volume 2 Springer/Verlag. https://doi.org/ 10.1007/978-3-319-94779-2_3
  • Riper, H., Hoogendoorn, A., Cuijpers, P., Karyotaki, E., Boumparis, N., Mira, A., et al. (2018) Effectiveness and treatment moderators of internet interventions for adult problem drinking: An individual patient data meta-analysis of 19 randomised controlled trials. PLoS Medicine, 15(12): e1002714. https://doi.org/10.1371/journal.pmed.1002714
  • Rocha, A., Camacho, R., Ruwaard, J., & Riper, H. (2018). Using multi-relational data mining to discriminate blended therapy efficiency on patients based on log data. Internet Interventions, 12, 176-180. https://doi.org/10.1016/j.invent.2018.03.003
  • Titzler, I., Saruhanjan, K., Berking, M., Riper, H., & Ebert, D. D. (2018). Barriers and facilitators for the implementation of blended psychotherapy for depression: A qualitative pilot study of therapists’ perspective. Internet Interventions, 12, 150-164. https://doi.org/10.1016/j.invent.2018.01.002
  • Urech, A., Krieger, T., Möseneder, L., Biaggi, A., Vincent, A., Poppe, C., Meyer, B., Riper, H., & Berger, T. (2018). A patient post-hoc perspective on advantages and disadvantages of blended treatment for depression: A qualitative content analysis. Psychotherapy Research, 1 – 13https://doi.org/10.1080/10503307.2018.1430910
  • Van Breda, W., Bremer, V., Becker, D., Hoogendoorn, M., Funk, B., Ruwaard, J., & Riper, H. (2018). Predicting therapy success for treatment as usual and blended treatment in the domain of depression. Internet interventions12, 100-104. https://doi.org/10.1016/j.invent.2017.08.003
  • Vara, M. D., Herrero, R., Etchemendy, E., Espinoza, M., Baños, R. M., Garcia-Palacios, A., Lera, G., Folch, B., Palop-Larrea, V., Vázquez, P., Franco-Martín, M., Kleiboer, A., Riper, H., & Botella, C. (2018). Efficacy and cost-effectiveness of a blended cognitive behavioral therapy for depression in Spanish primary health care: study protocol for a randomised non-inferiority trial. BMC Psychiatry, 18(74). https://doi.org/10.1186/s12888-018-1638-6
  • Vernmark, K., Hesser, H., Topooco, N., Berger, T., Riper, H., Luuk, L., Backlund, L., Carlbring, P., & Andersson, G. (2018). Working alliance as a predictor of change in depression during blended cognitive behaviour therapy. Cognitive Behaviour Therapy, 47(1), 1-5. https://doi.org/10.1080/16506073.2018.1533577
  • Vis, C., Mol, M., Kleiboer, A., Bührmann, L., Finch, T., Smit, J., & Riper, H. (2018). Improving implementation of eMental health for mood disorders in routine practice: Systematic review of barriers and facilitating factors. JMIR Mental Health5(1), e20. https://doi.org/10.2196/mental.9769
  • Weisel, K. K., Lehr, D., Heber, E., Zarski, A. C., Berking, M., Riper, H., & Ebert, D. D. (2018). Severely burdened individuals do not need to be excluded from internet-based and mobile-based stress management: Effect modifiers of treatment outcomes from three randomized controlled trials. Journal of Medical Internet Research20(6), e211. https://doi.org/10.2196/jmir.9387

Publications in 2017

  • Boß, L., Lehr, D., Schaub, M. P., Castro, R. P, Riper, H., Berking, M., & Ebert, D. D. (2017). Efficacy of a web‐based intervention with and without guidance for employees with risky drinking: results of a three‐arm randomized controlled trial. Addiction, 113(4), 635-646. https://doi.org/10.1111/add.14085
  • Boumparis, N., Karyotaki, E., Schaub, M. P., Cuijpers, P., & Riper, H. (2017). Internet interventions for adult illicit substance users: A meta‐analysis. Addiction, 112(9),1521-1532. https://doi.org/10.1111/add.13819
  • Buntrock, C., Berking, M., Smit, F., Lehr, D., Nobis, S., Riper, H., Cuijpers, P., & Ebert, D. D. (2017). Preventing depression in adults with subthreshold depression: Health-economic evaluation alongside a pragmatic randomized controlled trial of a web-based intervention. Journal of Medical Internet Research19(1), e5. https://doi.org/10.2196/jmir.6587
  • Carlbring, P., Andersson, G., Cuijpers, P., Riper, H., & Hedman-Lagerlöf, E. (2017). Internet-based vs. face-to-face cognitive behavior therapy for psychiatric and somatic disorders: An updated systematic review and meta-analysis. Cognitive Behaviour Therapy47(1), 1-18. https://doi.org/10.1080/16506073.2017.1401115
  • Cuijpers, P., Kleiboer, A., Karyotaki, E., & Riper, H. (2017). Internet and mobile interventions for depression: Opportunities and challenges. Depression and Anxiety, 34(7), 596-602. https://doi.org/10.1002/da.22641
  • Ebert, D. D., Kählke, F., Buntrock, C., Berking, M., Smit, F., Heber, E., Baumeister, H., Funk, B., Riper, H., & Lehr, D. (2017). A health economic outcome evaluation of an internet-based mobile-supported stress management intervention for employees. Scandinavian Journal of Work, Environment & Health, 44(2), 171-182. https://doi.org/10.5271/sjweh.3691
  • Ebert, D. D., Nobis, S., Lehr, D., Baumeister, H., Riper, H., Auerbach, R. P., Snoek, F., Cuijpers, P., & Berking, M. (2017). The 6-month effectiveness of internet-based guided self-help for depression in adults with type 1 and 2 diabetes mellitus. Diabetic Medicine34(1), 99-107. https://doi.org/10.1111/dme.13173
  • Erbe, D., Eichert, H. C., Riper, H., & Ebert, D. D. (2017). Blending face-to-face and internet-based interventions for the treatment of mental disorders in adults: Systematic review. Journal of Medical Internet Research19(9), e306. https://doi.org/10.2196/jmir.6588
  • Heber, E., Ebert, D. D., Lehr, D., Cuijpers, P., Berking, M., Nobis, S., & Riper, H. (2017). The benefit of web- and computer-based interventions for stress: A systematic review and meta-analysis. Journal of Medical Internet Research, 19(2), e32. https://doi.org/10.2196/jmir.5774
  • Karyotaki, E., Riper, H., & Cuijpers, P. (2017). Internet-based self-help interventions for depression in routine care—Reply. JAMA Psychiatry, 74(8), 853. https://doi.org/10.1001/jamapsychiatry.2017.1406
  • Karyotaki, E., Riper, H., Twisk, J., Hoogendoorn, A., Kleiboer, A., Mira, A., . . . & Cuijpers, P. (2017). Efficacy of self-guided internet-based cognitive behavioral therapy in the treatment of depressive symptoms: A meta-analysis of individual participant data. JAMA Psychiatry, 74(4), 351-359. https://doi.org/10.1001/jamapsychiatry.2017.0044
  • Kolovos, S., Bosmans, J. E., Riper, H., Chevreul, K., Coupé, V. M., & van Tulder, M. W. (2017). Model-based economic evaluation of treatments for depression: A systematic literature review. PharmacoEconomics-Open1(3), 1-17. https://doi.org/10.1007/s41669-017-0014-7
  • Kolovos, S., Bosmans, J. E., van Dongen, J. M., van Esveld, B., Magai, D., van Straten, A., van der Feltz-Cornelis, C., van Steenbergen-Weijenburg, K. M., Huijbregts, K. M., van Marwijk, H., Riper, H., & van Tulder, M. W. (2017). Utility scores for different health states related to depression: Individual participant data analysis. Quality of Life Research, 26(7), 1649-1658. https://doi.org/10.1007/s11136-017-1536-2
  • Kolovos, S., van Tulder, M. W., Cuijpers, P., Prigent, A., Chevreul, K., Riper, H., & Bosmans, J. E. (2017). The effect of treatment as usual on major depressive disorder: A meta-analysis. Journal of Affective Disorders210, 72-81. https://doi.org/10.1016/j.jad.2016.12.013. Review.
  • Lau, H. M., Smit, J. H., Fleming, T. M., & Riper, H. (2017). Serious Games for mental health: Are they accessible, feasible, and effective? A systematic review and meta-analysis. Frontiers in Psychiatry7, 209. https://doi.org/10.3389/fpsyt.2016.00209. Review.
  • Lin, J., Sander, L., Paganini, S., Schlicker, S., Ebert, D., Berking, M., … & Riper, H. (2017). Effectiveness and cost-effectiveness of a guided internet- and mobile-based depression intervention for individuals with chronic back pain: Protocol of a multi-centre randomised controlled trial. BMJ Open7(12), e015226. https://doi.org/10.1136/bmjopen-2016-015226
  • Provoost, S., Lau, H. M., Ruwaard, J., & Riper, H. (2017). Embodied conversational agents in clinical psychology: A scoping review. Journal of Medical Internet Research19(5), e151. https://doi.org/10.2196/jmir.6553
  • Topooco, N., Riper, H., Araya, R., Berking, M., Brunn, M., Chevreul, K., … & Andersson, G. (2017). Attitudes towards digital treatment for depression: A European stakeholder survey. Internet Interventions, 8, 1-9https://doi.org/10.1016/j.invent.2017.01.001
  • van de Ven, P., O’Brien, H., Henriques, R., Klein, M., Msetfi, R., Nelson, J., … & Riper, H., on behalf of the E-COMPARED Consortium. (2017). ULTEMAT: A mobile framework for smart ecological momentary assessments and interventions. Internet Interventions9, 74-81. https://doi.org/10.1016/j.invent.2017.07.001

Publications in 2016

  • Asselbergs, J., Ruwaard, J., Ejdys, M., Schrader, N., Sijbrandij, M., & Riper, H. (2016) Mobile phone-based unobtrusive ecological momentary assessment of day-to-day mood: An explorative study. Journal of Medical Internet Research, 18(3), e72. https://doi.org/10.2196/jmir.5505
  • Becker, D., Bremer, V., Funk, B., Asselbergs, J., Riper, H., & Ruwaard, J. (2016, August). How to predict mood? Delving into features of smartphone-based data. In Proceedings of the Twenty-second Americas Conference on Information Systems (AMCIS). San Diego, USA: AIS electronic library, 2016. Link
  • Bijker, L., Kleiboer, A., Riper, H., Cuijpers, P., & Donker, T. (2016). E-care 4 caregivers – an online intervention for nonprofessional caregivers of patients with depression: Study protocol for a pilot randomized controlled trial. Trials, 17(1), 193. https://doi.org/10.1186/s13063-016-1320-6
  • Boß, L., Lehr, D., Reis, D., Vis, C., Riper, H., Berking, M., & Ebert, D. D. (2016) Reliability and validity of assessing user satisfaction with web-based health interventions. Journal of Medical Internet Research, 18(8), e234. https://doi.org/10.2196/jmir.5952
  • Buntrock, C., Ebert, D. D., Lehr, D., Smit, F., Riper, H., Berking, M., & Cuijpers, P. (2016). Effect of a web-based guided self-help intervention for prevention of major depression in adults with subthreshold depression: A randomized clinical trial. JAMA, 315(17), 1854-1863. https://doi.org/10.1001/jama.2016.4326
  • Ebert, D. D., Donkin, L., Andersson, G., Andrews, G., Berger, T., Carlbring, P., Rozenthal, A., Choi, I., Laferton, J. A., Johansson, R., Kleiboer, A., Lange, A., Lehr, D., Reins, J. A., Funk, B., Newby, J., Perini, S., Riper, H., Ruwaard, J., Sheeber, L., Snoek, F. J., Titov, N., Ünlü Ince, B., van Bastelaar, K., Vernmark, K., van Straten, A., Warmerdam, L., Salsman, N., & Cuijpers, P. (2016). Does internet-based guided-self-help for depression cause harm? An individual participant data meta-analysis on deterioration rates and its moderators in randomized controlled trials. Psychological Medicine, 46(13), 2679-2693. https://doi.org/10.1017/S0033291716001562
  • Ebert, D. D., Heber, E., Berking, M., Riper, H., Cuijpers, P., Funk, B., & Lehr, D. (2016). Self-guided internet-based and mobile-based stress management for employees: Results of a randomised controlled trial. Occupational and Environmental Medicine, 73(5), 315-323. https://doi.org/10.1136/oemed-2015-103269
  • Ebert, D. D., Lehr, D., Heber, E., Riper, H., Cuijpers, P., & Berking, M. (2016) Internet- and mobile-based stress management for employees with adherence-focused guidance: Efficacy and mechanism of change. Scandinavian Journal of Work, Evironment & Health, 42(5), 382-394. https://doi.org/10.5271/sjweh.3573
  • Ebert, D. D., Nobis, S., Lehr, D., Baumeister, H., Riper, H., Auerbach, R. P., Snoek, F., Cuijpers, P., & Berking, M. (2016). The 6-month effectiveness of internet-based guided self-help for depression in adults with type 1 and 2 diabetes mellitus. Diabetic Medicine, 34(1), 99-107. https://doi.org/10.1111/dme.13173
  • Fleming, T. M., de Beurs, D., Khazaal, Y., Gaggioli, A., Riva, G., Botella, C., Baños, R. M., Aschieri, F., Bavin, L. M., Kleiboer, A., Merry, S., Lau, H. M., & Riper, H. (2016). Maximizing the impact of e-therapy and serious gaming: Time for a paradigm shift. Frontiers in Psychiatry, 7, 65. https://doi.org/10.3389/fpsyt.2016.00065. eCollection 2016. Review.
  • Heber, E., Lehr, D., Ebert, D. D., Berking, M., & Riper, H. (2016). Web-based and mobile stress management intervention for employees: A randomized controlled trial. Journal of Medical Internet Research, 18(1), e21. https://doi.org/10.2196/jmir.5112
  • Kemmeren, L. L., van Schaik, D. J., Riper, H., Kleiboer, A. M., Bosmans, J. E., & Smit, J. H. (2016). Effectiveness of blended depression treatment for adults in specialised mental healthcare: Study protocol for a randomised controlled trial. BMC Psychiatry, 16(1), 113. https://doi.org/10.1186/s12888-016-0818-5
  • Kleiboer, A., Smit, J., Bosmans, J., Ruwaard, J., Andersson, G., Topooco, N., … & Riper, H. (2016). European COMPARative Effectiveness research on blended Depression treatment versus treatment-as-usual (E-COMPARED): Study protocol for a randomized controlled, non-inferiority trial in eight European countries. Trials, 17(1), 387. https://doi.org/10.1186/s13063-016-1511-1
  • Kooistra, L. C., Ruwaard, J., Wiersma, J. E., van Oppen, P., van der Vaart, R., van Gemert-Pijnen, L., & Riper, H.(2016). Development and initial evaluation of blended cognitive behavioural treatment for major depression in routine specialized mental health care. Internet Interventions, 4, 61-71. https://doi.org/10.1016/j.invent.2016.01.003
  • Mathiasen, K., Andersen, T. E., Riper, H., Kleiboer, A. A., & Roessler, K. K. (2016). Blended CBT versus face-to-face CBT: A randomised non-inferiority trial. BMC Psychiatry, 16(1), 432. https://doi.org/10.1186/s12888-016-1140-y
  • Mathiasen, K., Riper, H., Ehlers, L. H., Valentin, J. B., & Rosenberg, N. K. (2016). Internet-based CBT for social phobia and panic disorder in a specialised anxiety clinic in routine care: Results of a pilot randomised controlled trial. Internet Interventions, 4, 92-98. https://doi.org/10.1016/j.invent.2016.03.001
  • Mol, M., Dozeman, E., van Schaik, D. J., Vis, C. P., Riper, H., & Smit, J. H. (2016). The therapist’s role in the implementation of internet-based cognitive behavioural therapy for patients with depression: Study protocol. BMC Psychiatry, 16(1), 338. https://doi.org/10.1186/s12888-016-1045-9
  • Nobis, S., Lehr, D., Berking, M., Baumeister, H., Riper, H., Snoek, F., & Ebert, D. D. (2016). Langzeiteffekte eines Online-Trainings zur Reduktion von depressiven Beschwerden für Personen mit Diabetes Mellitus Typ 1 und Typ 2 – Ergebnisse einer randomisiert-klinischen Studie nach 12 Monaten. Diabetologie und Stoffwechsel, 11(S 01), 89. https://doi.org/10.1055/s-0036-1580836
  • Patrick, K., Hekler, E. B., Estrin, D., Mohr, D. C., Riper, H., Crane, D., Godino, J., & Riley, W. T. (2016). The pace of technologic change: Implications for digital health behavior intervention research. American Journal of Preventive Medicine, 51(5), 816-824. https://doi.org/10.1016/j.amepre.2016.05.001
  • Riper, H., & Cuijpers, P. J. (2016). Telepsychology and eHealth. In J. C. Norcross, G. R. VandenBos, D. K. Freedheim, & R. Krishnamurthy (Eds.), APA handbook of clinical psychology: Applications and methods (pp. 451–463). American Psychological Association. https://doi.org/10.1037/14861-024
  • Schaub, M. P., Blankers, M., Lehr, D., Boss, L., Riper, H., Dekker, J., Goudriaan, A. E., Maier, L. J., Haug, S., Amann, M., Dey, M., Wenger, A., & Ebert, D. D. (2016). Efficacy of an internet-based self-help intervention to reduce co-occurring alcohol misuse and depression symptoms in adults: Study protocol of a three-arm randomised controlled trial. BMJ Open, 6(5), e011457. https://doi.org/10.1136/bmjopen-2016-011457
  • Schuurmans, J., Van der Linden, J. L., Van Ballegooijen, W., Ruwaard, J., Stek, M. L., Smit, J. H., & Riper, H. (2016). Tablet-based support for older adults with severe mood disorders treated in an ambulatory geriatric psychiatry setting: Protocol of a feasibility study of the eCare@Home platform. Internet Interventions, 6, 22–28. https://doi.org/10.1016/j.invent.2016.09.001
  • Thiart, H., Ebert, D. D., Lehr, D., Nobis, S., Buntrock, C., Berking, M., Smit, F., & Riper, H. (2016). Internet-based cognitive behavioral therapy for insomnia: A health economic evaluation. Sleep, 39(10), 1769. https://doi.org/10.5665/sleep.6152
  • van Ballegooijen, W., Riper, H., Cuijpers, P., van Oppen, P., & Smit, J. H. (2016). Validation of online psychometric instruments for common mental health disorders: A systematic review. BMC Psychiatry, 16(1), 45. https://doi.org/10.1186/s12888-016-0735-7.
  • van Ballegooijen, W., Ruwaard, J., Karyotaki, E., Ebert, D. D., Smit, J. H., & Riper, H. (2016). Reactivity to smartphone-based ecological momentary assessment of depressive symptoms (MoodMonitor): Protocol of a randomised controlled trial. BMC Psychiatry, 16(1), 359. https://doi.org/10.1186/s12888-016-1065-5
  • van Breda, W., Hoogendoorn, M., Eiben, A., Andersson, G., Riper, H., Ruwaard, J., & Vernmark, K. (2016, December). A feature representation learning method for temporal datasets. In Computational Intelligence (SSCI), 2016 IEEE Symposium Series on (pp. 1-8). IEEE Computer Society Press. https://doi.org/10.1109/SSCI.2016.7849890
  • van Breda, W., Pastor, J., Hoogendoorn, M., Ruwaard, J., Asselbergs, J., & Riper, H. (2016, June). Exploring and comparing machine learning approaches for predicting mood over time. In Chen, Y., Tanaka, S., Howlett, R. J., & Lakhmi, C. J. (Eds.), International Conference on Innovation in Medicine and Healthcare (pp. 37-47). Cham, Switzerland: Springer International Publishing
  • Yardley, L., Spring, B. J., Riper, H., Morrison, L. G., Crane, D. H., Curtis, K., Merchant, G. C., Naughton, F., & Blandford, A. (2016). Understanding and promoting effective engagement with digital behavior change interventions. American Journal of Preventive Medicine, 51(5), 833-842. https://doi.org/10.1016/j.amepre.2016.06.015
  • Zarski, A. C., Lehr, D., Berking, M., Riper, H., Cuijpers, P., & Ebert, D. D. (2016). Adherence to internet-based mobile-supported stress management: A pooled analysis of individual participant data from three randomized controlled trials. Journal of Medical Internet Research, 18(6), e146. https://doi.org/10.2196/jmir.4493

Publications in 2015

  • Boß, L., Lehr, D., Berking, M., Riper, H., Schaub, M. P., & Ebert, D. D. (2015). Evaluating the (cost-)effectiveness of guided and unguided internet-based self-help for problematic alcohol use in employees, a three arm randomized controlled trial. BMC Public Health, 15(1), 1043. https://doi.org/10.1186/s12889-015-2375-0
  • Buntrock, C., Ebert, D. D., Lehr, D., Riper, H., Smit, F., Cuijpers, P., & Berking, M. (2015). Effectiveness of a web-based cognitive behavioural intervention for subthreshold depression: Pragmatic randomised controlled trial. Psychotherapy and Psychosomatics, 84(6), 348-358. https://doi.org/10.1159/000438673
  • Cuijpers, P. & Riper, H. (2015). Internet interventions for depressive disorders: An overview. Revista De Psicopatología y Psicología Clínica, 19(3), 209-216. https://doi.org/10.5944/rppc.vol.19.num.3.2014.13902
  • De Wit, J., Dozeman, E., Ruwaard, J., Alblas, J., & Riper, H. (2015). Web-based support for daily functioning of people with mild intellectual disabilities or chronic psychiatric disorders: A feasibility study in routine practice. Internet Interventions, 2(2), 161-168. https://doi.org/10.1016/j.invent.2015.02.007
  • Ebert, D. D., Berking, M., Thiart, H., Riper, H., Laferton, J. A., Cuijpers, P., Sieland, B., & Lehr, D. (2015). Restoring depleted resources: Efficacy and mechanisms of change of an internet-based unguided recovery training for better sleep and psychological detachment from work. Health Psychology, 34(S), 1240. https://doi.org/10.1037/hea0000277
  • Ebert, D. D., Zarski, A. C., Christensen, H., Stikkelbroek, Y., Cuijpers, P., Berking, M., & Riper, H. (2015). Internet and computer-based cognitive behavioral therapy for anxiety and depression in youth: A meta-analysis of randomized controlled outcome trials. PLoS One, 10(3), e0119895. https://doi.org/10.1371/journal.pone.0119895
  • Jones, M., Ebert, D. D., Jacobi, C., Beintner, I., Berger, T., Görlich, D., Schaub, M. P., Riper, H., Schmidt, U., Baños, R., Botella, C., & ICare Consortium (2015). Why didn’t patients use it? Engagement is the real story in Gilbody et al. (2015), not effectiveness. BMJ Online. LINK
  • Karyotaki, E., Kleiboer, A., Smit, F., Turner, D. T., Pastor, A. M., Andersson, G., Berger, T., Botella, C., Breton, J. M., Carlbring, P., Christensen, H., de Graaf, E., Griffiths, K., Donker, T., Farrer, L., Huibers, M. J., Lenndin, J., Mackinnon, A., Meyer, B., Moritz, S., Riper, H., Spek, V., Vernmark, K., & Cuijpers, P. (2015). Predictors of treatment dropout in self-guided web-based interventions for depression: An ‘individual patient data’ meta-analysis. Psychological Medicine, 45(13), 2717-2726. https://doi.org/10.1017/S0033291715000665
  • Kleiboer, A., Donker, T., Seekles, W., van Straten, A., Riper, H., & Cuijpers, P. (2015). A randomized controlled trial on the role of support in internet-based problem solving therapy for depression and anxiety. Behaviour Research and Therapy, 72, 63-71. https://doi.org/10.1016/j.brat.2015.06.013
  • Kok, G., Burger, H., Riper, H., Cuijpers, P., Dekker, J., van Marwijk, H., Smit, F., Beck, A., & Bockting, C. L. (2015). The three-month effect of mobile internet-based cognitive therapy on the course of depressive symptoms in remitted recurrently depressed patients: Results of a randomized controlled trial. Psychotherapy and Psychosomatics, 84(2), 90-99. https://doi.org/10.1159/000369469
  • Nobis, S., Ebert, D. D., Lehr, D., Riper, H., Snoek, F., Baumeister, H., & Berking, M. (2015). Langzeit-Effektivitäts-Analyse eines internetbasierten Programmes für Personen mit Diabetes mellitus Typ 1 und Typ 2 zur Reduktion von depressiven Beschwerden – Ergebnisse anhand einer randomisierten klinischen Studie. Diabetologie und Stoffwechsel 10(S 01), P136. https://doi.org/10.1055/s-0035-1549642
  • Nobis, S., Lehr, D., Ebert, D. D., Baumeister, H., Snoek, F., Riper, H., & Berking, M. (2015). Efficacy of a web-based intervention with mobile phone support in treating depressive symptoms in adults with type 1 and type 2 diabetes: A randomized controlled trial. Diabetes Care, 38(5), 776-783. https://doi.org/10.2337/dc14-1728
  • Romijn, G., Riper, H., Kok, R., Donker, T., Goorden, M., van Roijen, L. H., Kooistra, L., van Balkom, A., & Koning, J. (2015). Cost-effectiveness of blended vs. face-to-face cognitive behavioural therapy for severe anxiety disorders: Study protocol of a randomized controlled trial. BMC Psychiatry, 15(1), 311. https://doi.org/10.1186/s12888-015-0697-1
  • Thiart, H., Lehr, D., Ebert, D. D., Berking, M., & Riper, H. (2015). Log in and breathe out: Internet-based recovery training for sleepless employees with work-related strain – results of a randomized controlled trial. Scandinavian Journal of Work, Environment & Health, 41(2), 164-174. https://doi.org/10.5271/sjweh.3478
  • Vis, C., Kleiboer, A., Prior, R., Bønes, E., Cavallo, M., Clark, S. A., Dozeman, E., Ebert, D., Etzelmueller, A., Favaretto, G., Zabala, A. F., Kolstrup, N., Mancin, S., Mathiassen, K., Myrbakk, V. N., Mol, M., Jimenez, J. P., Power, K., van Schaik, A., Wright, C., Zanalda, E., Pederson, C. D., Smit, J., & Riper, H. (2015). Implementing and up-scaling evidence-based eMental health in Europe: The study protocol for the MasterMind project. Internet Interventions, 2(4), 399-409. https://doi.org/10.1016/j.invent.2015.10.002


Principal Investigator (PI and Co-PI) awarded 2012 – 2017

  • 2017 – 2021: IMPLEMENTALL. eMental-Health Implementation, H2020, VUA & OUH, total 6.000.000 Euro, VUA, inGeest, RUG, 1.500.000 Euro.
  • 2016 – 2020: CASPAR, Suicidepreventie, ZonMw, VUA & inGeest, 400.000 Euro.
  • 2016 – 2020: INTERREG, eMental-health and transnational implementation platform North-West Europe. ARQ & VUA, total 5.313.000 Euro, VUA 800.000 Euro.
  • 2016 – 2020: Kansen voor West, eGGZ Implementatie Centrum, ARQ & VUA, total 2.217.000 Euro, VUA 300.000 Euro.
  • 2015 – 2019: Horizon 2020 PHC 23 (CO-PI, 2 stage): Safe and efficient, prevention-oriented health and care systems (2 stage) total 6.000.000, VUA 280.000 Euro (Co-PI; PI: prof. Corinna Jacobi, Technical University Dresden, Germany).
  • 2015 – 2018: ZonMw Doelmatigheid, DO 2015 Type 2A. Cost-utility and cost-effectiveness of blended eHealth treatment for severe anxiety disorders in secondary mental health care. (PI: Altrecht; Co PI VUA/inGEEST in collaboration with prof. dr. T. van Balkom, PhD student VUA), 341 K).
  • 2014 – 2016: PI: European Commission 7th Framework Programme for Research: Comparative effectiveness research (CER) in health systems and health services interventions. FP7-HEALTH-2013-INNOVATION. E-COMPARED (European Comparative Effectiveness Research on Internet-based Depression Treatment. Budget: € 5.827.000 of which € 1,4 million for VUA/inGeest and 800.000 for Leuphana/Marburg University.
  • 2014 -2016: PI-NL: Commission of the European Communities, CIP, DG CONNECT, Brussels, Belgium. MASTERMIND: MAnagement of mental health diSorders Through advancEd technology and seRvices – teleHealth for the MIND. Budget total € 7.000.000 of which 600.000 for VUA/GGZinGeest and € 600.000 for Marburg University/ Schon Clinic.
  • 2012 – 2015: PI-NL: Commission of the European Communities, Ambient Assisted Living Program, Brussels, Belgium. eMentalCare – daily life management and monitoring system (platform/solution) for elderly with mental disorders. Budget: € 400.000. (VUA & GGZinGeest).
  • 2012 – 2015: PI: ZonMw, Netherlands Organisation for Health Research and Development, Health Care Efficiency Research. Blended care for depression. Budget: € 137.039.
  • 2012: PI: ZonMw, Netherlands Organisation for Health Research and Devel- opment, Prevention Program Mental Health, the Netherlands. State of the art eMental-health (‘kennissynthese 2012’). Budget: € 25.000.
  • 2012 – 2014: PI: Health Insurers Innovation Foundation (Innovatiefonds Zorgverzekeraars), the Netherlands. Pilot-study blended care for depression in secondary care. In collaboration with GGZinGeest and Twente University. Budget: € 150.000
  • 2012- 2013: PI: Pameijer, Regional Health Service for People with Disabilities, the Netherlands. Feasibility study on online blended support for persons with severe psychological disorders in guided independent living settings. Budget: € 45.000.
  • 2012 – 2013: PI: ZonMw, Netherlands Organisation for Health Research and Development, Prevention Program Mental Health, the Netherlands. ICT4DEPRESSION/ Moodbuster-Light for subclinical and moderate depression. Budget: € 100.000.

Keynotes & Presentations

Invited key notes only


  1. Riper, H. (2016, 13 April). Patient, Science & Value driven eMental-Health – the good, the bad the better. Palo Alto: Palo Alto University eHealth Day.
  2. Riper, H. (2016, 22 April). Patient, Science & Value driven eMental-Health: Good, Better, Best. Amsterdam: eHealth EU Conference: Visit European Health Officer.
  3. Riper, H. (2016, 28 April). Patient, Science & Technology Driven Mental-Health. Esjberg (DK): SOCIAL IMPACT Conference.
  4. Riper, H. (2016, 30 May). Keynote by Skype: Theory, Patient & Data Driven – eMental-Health Research. Odense (DK): Conference Telepsychiatry Centre.
  5. Riper, H. (2016, 9 June). eMental Health – Klinische- Kosten- en Ecologische Effectiviteit. Groningen: Opleidingsinstituut PPO.
  6. Riper, H. (2016, 19 August). Thumbing for Mental Health. Basel: 5th International Conference on Families and Children with Parental Mental Health Challenges.
  7. Riper, H. (2016, 16 September). Duimen voor Psychische Aandoeningen? Zeist: Cancer Survivorship Task Force Meeting.
  8. Riper, H. (2016, 16 October). ‘Thumbing’ for Mental Health. Utrecht: Mobile Health Care Conference.
  9. Riper, H. (2016, 13 October). Blending Science driven eMental-Health in to Routine Health Care. Amsterdam: Amsterdam Public Health Research Institute.
  10. Riper, H. (2016, 12 November). Spotify Mental-Health for Depression and Anxiety: Personalise, Engage and Connect. Dallas: Int. Society for Traumatic Stress Studies. 32 nd Annual meeting.
  11. Riper, H. (2016, 22 November). eMental-Health for Depression and Anxiety: Personalise, Engage and Connect. Barcelona: World of Health IT/HIMSS.
  12. Riper, H. (2016, 25 November). eHealth & Seksuologie: van sexting tot safe seks. Amersfoort: Lustrumcongres NVVS, TVS, VVS: Seks 2.0. Implementatie Congres
  13. Riper, H (2016, 1 December). eMental Health: Good, Bad, Better. Utrecht, eHealth


  1. Riper, H. (2015, 8 April). Preventie die beklijft: Onderzoek dat leidt, Technologie die verleidt, Integratie die verblijdt & de patient die begrijpt! Rotterdam: Nederlands Congres Volksgezondheid.
  2. Riper, H. (2015, 1 May). Onderzoek dat leidt, De patient die begrijpt, Technologie die verleidt, Preventie die beklijft! Amsterdam, Nederland: VUmc: Preconceptiezorg, quo vadis?
  3. Riper, H. (2015, 16 May). Personalise, Engage and Connect, eMental-health for Common Mental Disorders. Warsaw, Poland: SWPS, University.
  4. Riper, H. (2015, 4 June). Geen toekomst voor de GGZ zonder eMental-health. Feit of Fictie? Arnhem, Nederland: DISCURA.
  5. Riper, H. (2015, 3 July). Social Psychiatry in the Age of Informatics. Geneva, Switzerland: 2nd European Congress for Social Psychiatry.
  6. Riper, H. (2014, 8 July). eMental-Health, Quantifying Patients, Therapist & Communities. Amsterdam, the Netherlands: UvA, International Summer School Addictions.
  7. Riper, H. (2015, 25 September). Digitale Behandeling van Probleemdrinken: de Effectiviteit Voorbij. Zwolle, Nederland: Motiverende gespreksvoering in Nederland, Hogeschool Windesheim.
  8. Riper, H. (2015, 30 September). Patient, Science & Value driven eMental-Health. Badhof Gastein, Austria: 18th European Health Forum Gastein.
  9. Riper, H. (2015, 21 October). eMental-health, the good, the bad and the better. Odense, Denmark: European Telemedicine Conference.
  10. Riper, H. (2015, 14 October). Spotify eMental-Health: Personalise, Engage & Connect. Porto, Portugal: Stop Depression: Instituto Superior da Maia (ISMAI).
  11. Riper, H. (2015, 17 November). Spotify Mental Health: Personalise, Engage, Connect. Eindhoven: Healthy Lifestyle Solutions Conference: Philips Group Innovation, Research.
  12. Riper, H. (2015, 1 december). eMental-Health: Good, Bad, Better. Utrecht, Jaarbeurs: eHealth Implementatie Congres, Bohn Stafleu van Loghum.
  13. Riper, H. (2015, 10 December). eMental Health: Denken én Doen. Utrecht, Nederland: IMPREEZE.


My press appearances includes interviews for national television, radio and newspapers, magazines, websites and other national and international periodicals.

Press Highlights 2016

Press Highlights 2015

  • AD (29 december 2015) ‘Digitale behandeling razend populair in Nederland’. Marcia Nieuwenhuis.
  • NU.nl (29 december 2015) ‘Gebruik onlinetherapie gestegen in 2015’.
  • PZC (29 december 2015) ‘Hulp online groeit explosief’, Marcia Nieuwenhuis.
  • MindDistrict, Interview Heleen Riper, 15 years of eMental-health. Youtube: www.youtube.com/watch?v=qN00FKgXQUc (november 2015).
  • NPO Wetenschap, (4 november 2015) De Kennis van Nu: ‘Online gedragstherapie neemt hoge vlucht komende jaren’. Valentijn van der Lende.
  • Ad Valvas 3 (30 september 2015) ‘Therapeuten werken te weinig met nieuwe media.’ Welmoed Visser.
  • Smarthealth.nl: (10 september 2015) ‘Blog: de eerste hoogleraar e-Mental-Health in Nederland.’ Jorne Grolleman.
  • Counselling Magazine (8 september 2015) ‘Digitale psychologische hulpverlening nog beter in te zetten’.
  • Zorg &Welzijn (27 augustus 2015). ‘Digitale behandeling ggz biedt kansen’ Marianne Velsink.
  • GZ-psychologie 3 (april 2015) ‘Toekomst ggz ondenkbaar zonder eMental-health’ Jorn Hövels.
  • Cogis, Cogiscope 03 (maart 2015) ‘Implementatie van digitale zorg gaat langzaam.’ Maarten Dallinga.
  • Counselling Magazine: thema ‘E-Health’ (februari 2015) ‘Blended care heeft de toekomst’ Christine Beenhakker.

Press Highlights 2012 – 2014

  • Trouw (28 augustus 2014) ‘De psycholoog kijkt mee via internet’ Iris Pronk.
  • The Voice of the American Psychiatric Association and the Psychiatric Community (19 feb.2014) Equal Benefit for Minorities From Psychotherapy, Study Finds.
  • Leergang Sarphathi Initiatief, Academische Werkplaats Publieke Gezondheid (21 januari 2014). Interview met Heleen Riper “Smartphone is straks je toegang tot zorg” door Yvonne van Osch: http://sarfati.nl/?page_id=1114.
  • Young Gasteiners (2014). Blog, ‘Deploying eHealth, The time to hesitate is over!’ http://www.ehfg.org/conference.html.
  • European Parliament Magazine (22 Sept. 2014). Accelarating upscaling of eMental Health in Europe, H. Riper en J. Smit. 397, page 27. https://www.theparliamentmagazine.eu.
  • Altinget (velfaerdsteknologi, 9. december 2014) Ekspert, Heleen Riper: Online-behandling løser Sundhedsudfordringer.
  • Parliament magazine: https://www.theparliamentmagazine.eu/ : page 27/ issue397/22 Sept. 2014
  • PsychoPraktijk, december 2013 (6, nr. 5). Interview met Heleen Riper: ‘Blended behandelingen bepalen het komende e-mental health tijdperk’: 6 – 7.
  • Tracer (VUMC), november 2013. Blended care voor depressie, interview Heleen Riper.
  • Volkskrant, 30 oktober 2013, Geestelijke zorg kiest steeds vaker voor onlinehulp.
  • inDrukken (GGZ inGeest), juni 2013. ‘Een teachable moment via de smartphone-app’, interview met Heleen Riper.
  • Tracer (VUMC), juni 2013. Blended care voor depressie, interview Heleen Riper.
  • Zorgvisie / ICT, maart 2013, special issue Zorg & ICT beurs. Interview met Heleen Riper: ‘Elke zorginstelling beseft dat de toekomst bij e-health ligt’ door Mario Gibbels (cover story).
  • Zorgvisie/ ICT.Kennissynthese eMental-Health (2013): http://www.zorgvisie.nl/ICT/Nieuws/2013/5/Preventie-psychische-problemen-zonder-e-health-ondenkbaar-1271137W/
  • Algemeen Dagblad, 13 december 2012, Internettherapie vermindert suïcidegedachtes onder depressieve patiënten. Ingezonden brief: P. Cuijpers, H. Riper en F. Schalken.
  • UWV Magazine, Aan het lijntje gehouden (en toch geholpen), mei 2012.
  • Radiointerview: OBA Live – 2 mei 2012. Theodor Holman in gesprek met de hoofdgast van de avond Heleen Riper, over psychische zorg op afstand.
  • Zuidas Amsterdam, maart 2012, interview (http://www.zuidas.nl/interviews).
  • Plus Magazine, 12 februari 2012, M. v. Santen – Heleen Riper, interview.
  • Frankwatching.com: Wybo Vons, interview met Heleen Riper, 26 januari 2012 (www.frankwatching.com/archive/2012/).